Tag Archives: Evolution

News

New study: function found for beta-globin pseudogene that was labeled “junk” during Dover trial

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Casey Luskin tells us about a new study in Evolution News.

Excerpt:

A new paper in Genome Biology and Evolution argues that the famous beta-globin pseudogene is functional. Why is this pseudogene famous?

Well, it’s been Exhibit A — literally, offered as evidence in a court case — for critics of intelligent design who argue that our genome is full of useless, functionless junk, and therefore can’t be a product of design. Near the beginning of his testimony on the very first day of the 2005 Kitzmiller v. Dover trial, Brown University biology professor Kenneth Miller testified to the court that the beta-globin pseudogene is “broken, and it has a series of molecular errors that render the gene non-functional.” (Day 1 AM, p. 79.) He further told the court:

And the fact that all three of these species have matching mistakes leads us to just one conclusion, and that’s the same conclusion that Charles Darwin predicted almost a century and a half ago, and that is that these three species share a common ancestor. Matching mistakes are evidence of common ancestry. (Day 1 AM, p. 81)

In his 2008 book Only a Theory, Miller is even more explicit in asserting that this pseudogene refutes intelligent design. He writes that “A detailed analysis of the beta-globin pseudogene shows a series of mutations have rendered it nonfunctional” (p. 102). In Miller’s view, that takes care of ID:

The gorilla and chimpanzee pseudogenes have exactly the same set of molecular errors [in their beta-globin pseudogene] … There’s no escaping the implication of these matching mistakes, and there’s no point in arguing that six identical mistakes could have turned up independently in three unrelated species. The only sensible interpretation is that the original errors developed at random in a single common ancestor of these three species. In a court of genetic copyright law, any motion that a designer could claim originality for the human genome would be tossed out in a flash. (pp. 102-103)

Now a new paper in Genome Biology and Evolution, “Evolutionary Constraints in the β-Globin Cluster: The Signature of Purifying Selection at the δ-Globin (HBD) Locus and Its Role in Developmental Gene Regulation, argues that the beta-globin pseudogene is not broken, but in fact performs an important function in regulating gene expression.

Remember, Darwinists are still reeling from the ENCODE study that found that the non-coding DNA that they said was 100% junk was actually 80% functional. The trouble is that they are always letting their philosophy of naturalism get in the way of their science. They assume that nature is all there is. They assumed that everything is not designed. Then they are quick to say that things that aren’t junk are junk, in order to confirm their assumption. Problems occur later when good science comes along and proves their philosophical assumption of naturalism wrong. Do they then give up the philosophical assumption? Heck no – that’s their religion! But they ought to give it up if they were honest, and stick with the science instead. Too much bad religion among the Darwinists – that’s the problem.

Videos

What is intelligent design? Dr. Stephen C. Meyer explains the theory

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A MUST-SEE lecture based on Dr. Stephen C. Meyer’s book “Signature in the Cell“.

You can get an MP3 of the lecture here. (30 MB)

I highly recommend watching the lecture, and looking at the slides. The quality of the video and the content is first class. There is some Q&A (9 minutes) at the end of the lecture.

Topics:

  • intelligent design is concerned with measuring the information-creating capabilities of natural forces like mutation and selection
  • Darwinists think that random mutations and natural selection can explain the origin and diversification of living systems
  • Darwinian mechanisms are capable of explaining small-scale adaptive changes within types of organisms
  • but there is skepticism, even among naturalists, that Darwinian mechanisms can explain the origin of animal designs
  • even if you concede that Darwinism can account for all of the basic animal body plans, there is still the problem of life’s origin
  • can Darwinian mechanisms explain the origin of the first life? Is there a good naturalistic hypothesis to explain it?
  • there are at least two places in the history of life where new information is needed: origin of life, and Cambrian explosion
  • overview of the structure of DNA and protein synthesis (he has helpful pictures and he uses the snap lock blocks, too)
  • the DNA molecule is composed of a sequence of proteins, and the sequence is carefully selected to have biological function
  • meaningful sequences of things like computer code, English sentences, etc. require an adequate cause
  • it is very hard to arrive at a meaningful sequence of a non-trivial length by randomly picking symbols/letters
  • although any random sequence of letters is improbable, the vast majority of sequences are gibberish/non-compiling code
  • similarly, most random sequences of amino acids are lab-proven (Doug Axe’s work) to be non-functional gibberish
  • the research showing this was conducted at Cambridge University and published in the Journal of Molecular Biology
  • so, random mutation cannot explain the origin of the first living cell
  • however, even natural selection coupled with random mutation cannot explain the first living cell
  • there must already be replication in order for mutation and selection to work, so they can’t explain the first replicator
  • but the origin of life is the origin of the first replicator – there is no replication prior to the first replicator
  • the information in the first replicator cannot be explained by law, such as by chemical bonding affinities
  • the amino acids are attached like magnetic letters on a refrigerator
  • the magnetic force sticks the letters ON the fridge, but they don’t determine the specific sequence of the letters
  • if laws did determine the sequence of letters, then the sequences would be repetitive
  • the three materialist explanations – chance alone, chance and law, law alone – are not adequate to explain the effect
  • the best explanation is that an intelligent cause is responsible for the biological explanation in the first replicator
  • we know that intelligent causes can produce functional sequences of information, e.g. – English, Java code
  • the structure and design of DNA matches up nicely with the design patterns used by software engineers (like WK!)

There are some very good tips in this lecture so that you will be able to explain intelligent design to others in simple ways, using everyday household items and children’s toys to symbolize the amino acids, proteins, sugar phosphate backbones, etc.

Proteins are constructed from a sequence of amino acids:

A sequence of amino acids forming a protein
A sequence of amino acids forming a protein

Proteins sticking onto the double helix structure of DNA:

Some proteins sticking onto the sugar phosphate backbone
Some proteins sticking onto the sugar phosphate backbone

I highly, highly recommend this lecture. You will be delighted and you will learn something.

Here is an article that gives a general overview of how intelligent design challenges. If you want to read something more detailed about the material that he is covering in the lecture above related to the origin of life, there is a pretty good article here.

Related posts

Podcasts

Brian Auten interviews Dr. Angus Menuge on philosophy of mind

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Click here for the interview. It’s up at Apologetics 315!

Details:

Today’s interview is with Dr. Angus Menuge, Professor of Philosophy  at Concordia University, and author of Agents Under Fire: Materialism and the Rationality of Science. He talks about his background and work, the philosophy of mind, what reason (or reasoning) is, what materialism is as a worldview, things excluded from a materialistic worldview, methodological naturalism and materialism, accounting for free will, materialistic accounts of reason, the epistemological argument from reason, the ontological argument from reason, finding the best explanation for reason, problems with methodological naturalism, implications of materialism, practical application of the argument from reason, advice for apologists, the International Academy of Apologetics, and more.

If what Dr. Menuge says in this interview is true, and I think it is, then a person who believes in materialism can neither ground free will nor rationality! So atheism wouldn’t really be freethought so much as it would be… un-free… non-thought.

In case people don’t want to listen to the podcast, then I’ve got some things for you to read below.

The ontological argument from reason

Dr. Menuge presented a paper at the real Evangelical Philosophical Society conference for students and professors of philosophy, and you can download the paper here in Word format. (here’s a PDF version I made)

Here is the introduction to the paper that Dr. Menuge read at the EPS conference:

The argument from reason is really a family of arguments to show that reasoning is incompatible with naturalism. Here, naturalism is understood as the idea that foundationally, there are only physical objects, properties and relations, and anything else reduces to, supervenes on, or emerges from that. For our purposes, one of the most important claims of naturalism is that all causation is passive, automatic, event causation (an earthquake automatically causes a tidal wave; the tidal wave responds passively): there are no agent causes, where something does not happen automatically but only because the agent exerts his active power by choosing to do it. The most famous version of the argument from reason is epistemological: if naturalism were true, we could not be justified in believing it. Today, I want to focus on the ontological argument from reason, which asserts that there cannot be reasoning in a naturalistic world, because reasoning requires libertarian free will, and this in turn requires a unified, enduring self with active power.

The two most promising ways out of this argument are: (1) Compatibilism—even in a deterministic, naturalistic world, humans are capable of free acts of reason if their minds are responsive to rational causes; (2) Libertarian Naturalism—a self with libertarian free will emerges from the brain. I argue that neither of these moves works, and so, unless someone has a better idea, the ontological argument from reason stands.

The paper is 11 pages long, and it is helpful for those of you looking for some good discussion of one of the issues in the area of philosophy of mind.

You may also be interested in Alvin Plantinga’s epistemological argument from reason, which is related to this argument. It shows that even to have the ability to think, you have to have a certain anthropology and you have to have mental faculties that are designed for reason, not survival.

Methodological naturalism

Dr. Menuge also wrote an article entitled “Is methodological materialism good for science?”.

Intro:

Should science by governed by methodological materialism? That is, should scientists assume that only undirected causes can figure in their theories and explanations? If the answer to these questions is yes, then there can be no such thing as teleological science or intelligent design. But is methodological materialism a defensible approach to science, or might it prevent scientists from discovering important truths about the natural world? In my contribution to The Waning of Materialism (Oxford University Press, 2010), edited by Robert Koons and George Bealer, I consider twelve of the most common arguments in favor of methodological materialism and show that none of them is convincing.

Of these arguments, perhaps the most prevalent is the “God of the gaps” charge, according to which invoking something other than a material cause is an argument from ignorance which, like a bad script writer, cites a deus ex machina to save our account from difficulty. Not only materialists, but also many Christian thinkers, like Francis Collins, worry that appeal to intelligent design commits the God of the gaps fallacy.

As I argue, however, not only is an inference to an intelligent cause not the same as an inference to the supernatural, it is a mistake to assume that all gap arguments are bad, or that only theists make them. If a gap argument is based solely on ignorance of what might explain some phenomenon, then indeed it is a bad argument. But there are many good gap arguments which are made both by scientific materialists and proponents of intelligent design.

So how do you make an argument like that?

As Stephen Meyer has argued in his Signature in the Cell, intelligent design argues in just the same way, claiming not merely that the material categories of chance and necessity (singly or in combination) are unable to explain the complex specified information in DNA, but also that in our experience, intelligent agents are the only known causes of such information. The argument is based on what we know about causal powers, not on what we do not know about them.

Since the inference is based on known causal powers, we learn that the cause is intelligent, but only further assumptions or data can tell us whether that intelligence is immanent in nature or supernatural. It is a serious mistake to confuse intelligent design with theistic science, and the argument that since some proponents of design believe that the designer is God, that is what they are claiming can be inferred from the data, is a sophomoric intensional fallacy.

If you think this is interesting, then do have a listen to the podcast. Dr. Menuge is not an ordinary academic – he is very direct. He calls materialism “a catastrophe” in the podcast! Not a shrinking violet.