Tag Archives: Cell

News

Stephen C. Meyer lectures on intelligent design and the origin of life

Leave a comment

A MUST-SEE lecture based on Dr. Stephen C. Meyer’s book “Signature in the Cell“. One of my favorite 6 arguments for a Creator and Designer is the origin of the simplest replicating living system. When you look into the cell, what you’ll find is carefully sequenced components that for complex structures, like proteins. In this lecture, you’ll learn all about this “biological information”.

I highly recommend watching the lecture, and looking at the slides. The quality of the video and the content is first class. There is some Q&A (9 minutes) at the end of the lecture.

Topics:

  • intelligent design is concerned with measuring the information-creating capabilities of natural forces like mutation and selection
  • Darwinists think that random mutations and natural selection can explain the origin and diversification of living systems
  • Darwinian mechanisms are capable of explaining small-scale adaptive changes within types of organisms
  • but there is skepticism, even among naturalists, that Darwinian mechanisms can explain the origin of animal designs
  • even if you concede that Darwinism can account for all of the basic animal body plans, there is still the problem of life’s origin
  • can Darwinian mechanisms explain the origin of the first life? Is there a good naturalistic hypothesis to explain it?
  • there are at least two places in the history of life where new information is needed: origin of life, and Cambrian explosion
  • overview of the structure of DNA and protein synthesis (he has helpful pictures and he uses the snap lock blocks, too)
  • the DNA molecule is composed of a sequence of bases that code for proteins, and the sequence is carefully selected to have biological function
  • meaningful sequences of things like computer code, English sentences, etc. require an adequate cause
  • it is very hard to arrive at a meaningful sequence of a non-trivial length by randomly picking symbols/letters
  • although any random sequence of letters is improbable, the vast majority of sequences are gibberish/non-compiling code
  • similarly, most random sequences of amino acids are lab-proven (Doug Axe’s work) to be non-functional gibberish
  • the research showing this was conducted at Cambridge University and published in the Journal of Molecular Biology
  • so, random mutation cannot explain the origin of the first living cell
  • however, even natural selection coupled with random mutation cannot explain the first living cell
  • there must already be replication in order for mutation and selection to work, so they can’t explain the first replicator
  • but the origin of life is the origin of the first replicator – there is no replication prior to the first replicator
  • the information in the first replicator cannot be explained by law, such as by chemical bonding affinities
  • the amino acids are attached like magnetic letters on a refrigerator
  • the magnetic force sticks the letters ON the fridge, but they don’t determine the specific sequence of the letters
  • if laws did determine the sequence of letters, then the sequences would be repetitive
  • the three materialist explanations – chance alone, chance and law, law alone – are not adequate to explain the effect
  • the best explanation is that an intelligent cause is responsible for the biological explanation in the first replicator
  • we know that intelligent causes can produce functional sequences of information, e.g. – English, Java code
  • the structure and design of DNA matches up nicely with the design patterns used by software engineers (like WK!)

There are some very good tips in this lecture so that you will be able to explain intelligent design to others in simple ways, using everyday household items and children’s toys to symbolize the amino acids, proteins, sugar phosphate backbones, etc.

Proteins are constructed from a sequence of amino acids:

A sequence of amino acids forming a protein
A sequence of amino acids forming a protein

Proteins sticking onto the double helix structure of DNA:

Some proteins sticking onto the sugar phosphate backbone
Some proteins sticking onto the sugar phosphate backbone

I highly, highly recommend this lecture. You will be delighted and you will learn something.

Here is an article that gives a general overview of how intelligent design challenges. If you want to read something more detailed about the material that he is covering in the lecture above related to the origin of life, there is a pretty good article here.

There is a good breakdown of some of the slides with helpful flow charts here on Uncommon Descent.

Positive arguments for Christian theism

News

Does peer-reviewed research support a naturalistic origin of life?

4 Comments

So, on Friday night, there was a debate between Dr. James Tour and Professor Dave, an atheist with a bachelors degree who makes YouTube videos. The atheist spent his entire opening speech attacking Tour’s character. When Tour asked him to show him origin of life chemistry, he refused. The atheist shuffled through papers he apparently found by Googling, and read the titles. When asked what was in them, he said that he couldn’t remember.

But I was trying to decide who won the debate. There was one place where the atheist claimed that the early Earth had no molecular oxygen. He needs that to be true, in order for the chemistry that creates the building blocks of life to work. So I thought I would talk about a paper that refutes that. After my argument, I’ll talk about another mistake that the atheist made in the debate. Based on those two mistakes, I concluded that the atheist was speaking errors either intentionally or unintentionally, and therefore lost the debate.

Here’s a paper published in the prestigious peer-reviewed science journal Nature, entitled “The oxidation state of Hadean magmas and implications for early Earth’s atmosphere”.

Evolution News explains what the paper is about.

Excerpt:

A recent Nature publication reports a new technique for measuring the oxygen levels in Earth’s atmosphere some 4.4 billion years ago. The authors found that by studying cerium oxidation states in zircon, a compound formed from volcanic magma, they could ascertain the oxidation levels in the early earth. Their findings suggest that the early Earth’s oxygen levels were very close to current levels.

[…]Miller and Urey conducted experiments to show that under certain atmospheric conditions and with the right kind of electrical charge, several amino acids could form from inorganic compounds such as methane, ammonia, and water. Several experiments have been done using various inorganic starting materials, all yielding a few amino acids; however, one key aspect of all of these experiments was the lack of oxygen.

If the atmosphere has oxygen (or other oxidants) in it, then it is an oxidizing atmosphere. If the atmosphere lacks oxygen, then it is either inert or a reducing atmosphere. Think of a metal that has been left outside, maybe a piece of iron. That metal will eventually rust. Rusting is the result of the metal being oxidized. With organic reactions, such as the ones that produce amino acids, it is very important that no oxygen be present, or it will quench the reaction. Scientists, therefore, concluded that the early Earth must have been a reducing environment when life first formed (or the building blocks of life first formed) because that was the best environment for producing amino acids. The atmosphere eventually accumulated oxygen, but life did not form in an oxidative environment.

The problem with this hypothesis is that it is based on the assumption that organic life must have formed from inorganic materials. That is why the early Earth must have been a reducing atmosphere. Research has been accumulating for more than thirty years, however, suggesting that the early Earth likely did have oxygen present.

[…]Their findings not only showed that oxygen was present in the early Earth atmosphere, something that has been shown in other studies, but that oxygen was present as early as 4.4 billion years ago. This takes the window of time available for life to have begun, by an origin-of-life scenario like the RNA-first world, and reduces it to an incredibly short amount of time. Several factors need to coincide in order for nucleotides or amino acids to form from purely naturalistic circumstances (chance and chemistry). The specific conditions required already made purely naturalist origin-of-life scenarios highly unlikely. Drastically reducing the amount of time available, adding that to the other conditions needing to be fulfilled, makes the RNA world hypothesis or a Miller-Urey-like synthesis of amino acids simply impossible.

If you read the paper’s abstract, it finds that molecular oxygen would have been present by the end of the Hadean era. The earliest signs of life we have are from just after the end of the Hadean era. So, its undeniable that molecular oxygen was present. Did professor Dave lie, or was he just ignorant? One thing for sure, he pronounced that there was no oxygen in the same confident, insulting voice that he used for the rest of his presentation.

OK, so with that out of the way, Professor Dave also cited a paper in the journal Science. And there is an article on Creation.com by Johnathan Sarfati, who has a PhD in chemistry, about that very paper.

His post says:

It’s likely that the media reports you mention were referring to the paper in Science journal by Tracey Lincoln and Gerald Joyce.1 Quite often, the media hype just doesn’t match what was actually discovered. To be fair, Joyce, a well known chemical evolutionist, made it clear that he and his Ph.D. student Lincoln had not produced life, despite the headlines.2 Much earlier, Joyce admitted:

“The most reasonable assumption is that life did not start with RNA … . The transition to an RNA world, like the origins of life in general, is fraught with uncertainty and is plagued by a lack of experimental data.”3

Joyce and Lincoln started off with a fairly long RNA molecule. Given that nothing like RNA appears in Miller–Urey experiments, this already shows unjustified interference from an intelligent investigator. In fact, not even the building blocks, ribonucleotides, appear in such experiments, and they do not spontaneously form RNA. In fact, there are numerous chemical difficulties with obtaining RNA by blind undirected chemistry, the only sort allowed on the hypothetical primordial earth, as chemical evolutionist A.G. Cairns-Smith points out in his book Genetic Takeover4 (see extract at Cairns Smith: Detailed criticisms of the RNA world hypothesis). And it’s a huge step from RNA to the genetic code, its major use today.

Furthermore, this paper didn’t demonstrate replication but ligation—joining two small RNA pieces, previously designed to be a match to the longer strand. So this research already assumed not just one but three RNA strands. For this to be relevant to chemical evolution, the two pieces just by chance had to have pretty close to the complementary base pairs of the first piece—natural selection could not be invoked before reproduction.

Furthermore, since polymerization is unfavorable, the RNA pieces must be chemically activated in some way. Note that a catalyst merely accelerates the approach to equilibrium; it doesn’t change it (see diagram and explanation in Dino proteins and blood vessels: are they a big deal?). The paper states that one of the two joining RNA strands has a triphosphate group on the end. This is very reactive, so would be an unlikely component of a primordial soup, and would not last long even if it appeared. So a supply of matching activated RNA pieces likewise shows unacceptable investigator interference.

See also Does ribozyme research prove Darwinian evolution? for a critique of an earlier Joyce paper on alleged ribozyme evolution, as well as Self-replicating peptides? which has many similarities to the recent Joyce claim.

Now Tour seemed to let this problem drop in the debate. It just seems that Professor Dave was assuming from the titles of the papers that they were relevant to the problem of life. Well, scientists always sound optimistic in their papers. I know, I had to write one for my masters degree thesis, and it was published. That’s why you have to look at the data and be skeptical. Sadly Dave wasn’t able to be skeptical. He wanted something to be true, so he just didn’t bother to interact with challenges to his view. The whole problem with the origin of life is that there are many counter-factual conditions, experimenter interferences, etc. that have to be done to make things work at all. Dave reads the titles of papers, but he just isn’t aware of how the experimenters have adjusted the experiments in ways that are not true to the conditions on the early Earth.

Dr. Tour lost his temper and shouted a lot during the debate, so I don’t think the debate is worth watching. However, if you want to watch a good debate on the origin of life, try this one between Dr. Fazale Rana vs Dr. Michael Ruse. And if you want to see a good explanation of the sequencing problem, check out this lecture by Dr. Stephen C. Meyer. (who has also debated atheists who didn’t lie, shout or insult him – and they even had doctoral degrees)

News

Stephen C. Meyer lectures on intelligent design and the origin of life

Leave a comment

A MUST-SEE lecture based on Dr. Stephen C. Meyer’s book “Signature in the Cell“. One of my favorite 6 arguments for a Creator and Designer is the origin of the simplest replicating living system. When you look into the cell, what you’ll find is carefully sequenced components that for complex structures, like proteins. In this lecture, you’ll learn all about this “biological information”.

I highly recommend watching the lecture, and looking at the slides. The quality of the video and the content is first class. There is some Q&A (9 minutes) at the end of the lecture.

Topics:

  • intelligent design is concerned with measuring the information-creating capabilities of natural forces like mutation and selection
  • Darwinists think that random mutations and natural selection can explain the origin and diversification of living systems
  • Darwinian mechanisms are capable of explaining small-scale adaptive changes within types of organisms
  • but there is skepticism, even among naturalists, that Darwinian mechanisms can explain the origin of animal designs
  • even if you concede that Darwinism can account for all of the basic animal body plans, there is still the problem of life’s origin
  • can Darwinian mechanisms explain the origin of the first life? Is there a good naturalistic hypothesis to explain it?
  • there are at least two places in the history of life where new information is needed: origin of life, and Cambrian explosion
  • overview of the structure of DNA and protein synthesis (he has helpful pictures and he uses the snap lock blocks, too)
  • the DNA molecule is composed of a sequence of bases that code for proteins, and the sequence is carefully selected to have biological function
  • meaningful sequences of things like computer code, English sentences, etc. require an adequate cause
  • it is very hard to arrive at a meaningful sequence of a non-trivial length by randomly picking symbols/letters
  • although any random sequence of letters is improbable, the vast majority of sequences are gibberish/non-compiling code
  • similarly, most random sequences of amino acids are lab-proven (Doug Axe’s work) to be non-functional gibberish
  • the research showing this was conducted at Cambridge University and published in the Journal of Molecular Biology
  • so, random mutation cannot explain the origin of the first living cell
  • however, even natural selection coupled with random mutation cannot explain the first living cell
  • there must already be replication in order for mutation and selection to work, so they can’t explain the first replicator
  • but the origin of life is the origin of the first replicator – there is no replication prior to the first replicator
  • the information in the first replicator cannot be explained by law, such as by chemical bonding affinities
  • the amino acids are attached like magnetic letters on a refrigerator
  • the magnetic force sticks the letters ON the fridge, but they don’t determine the specific sequence of the letters
  • if laws did determine the sequence of letters, then the sequences would be repetitive
  • the three materialist explanations – chance alone, chance and law, law alone – are not adequate to explain the effect
  • the best explanation is that an intelligent cause is responsible for the biological explanation in the first replicator
  • we know that intelligent causes can produce functional sequences of information, e.g. – English, Java code
  • the structure and design of DNA matches up nicely with the design patterns used by software engineers (like WK!)

There are some very good tips in this lecture so that you will be able to explain intelligent design to others in simple ways, using everyday household items and children’s toys to symbolize the amino acids, proteins, sugar phosphate backbones, etc.

Proteins are constructed from a sequence of amino acids:

A sequence of amino acids forming a protein
A sequence of amino acids forming a protein

Proteins sticking onto the double helix structure of DNA:

Some proteins sticking onto the sugar phosphate backbone
Some proteins sticking onto the sugar phosphate backbone

I highly, highly recommend this lecture. You will be delighted and you will learn something.

Here is an article that gives a general overview of how intelligent design challenges. If you want to read something more detailed about the material that he is covering in the lecture above related to the origin of life, there is a pretty good article here.

There is a good breakdown of some of the slides with helpful flow charts here on Uncommon Descent.

Positive arguments for Christian theism