Tag Archives: Reason

Doug Axe explains the chances of getting a functional protein by chance

I’ve talked about Doug Axe before when I described how to calculate the odds of getting functional proteins by chance.

Let’s calculate the odds of building a protein composed of a functional chain of 100 amino acids, by chance. (Think of a meaningful English sentence built with 100 scrabble letters, held together with glue)

Sub-problems:

  • BONDING: You need 99 peptide bonds between the 100 amino acids. The odds of getting a peptide bond is 50%. The probability of building a chain of one hundred amino acids in which all linkages involve peptide bonds is roughly (1/2)^99 or 1 chance in 10^30.
  • CHIRALITY: You need 100 left-handed amino acids. The odds of getting a left-handed amino acid is 50%. The probability of attaining at random only L–amino acids in a hypothetical peptide chain one hundred amino acids long is (1/2)^100 or again roughly 1 chance in 10^30.
  • SEQUENCE: You need to choose the correct amino acid for each of the 100 links. The odds of getting the right one are 1 in 20. Even if you allow for some variation, the odds of getting a functional sequence is (1/20)^100 or 1 in 10^65.

The final probability of getting a functional protein composed of 100 amino acids is 1 in 10^125. Even if you fill the universe with pre-biotic soup, and react amino acids at Planck time (very fast!) for 14 billion years, you are probably not going to get even 1 such protein. And you need at least 100 of them for minimal life functions, plus DNA and RNA.

Research performed by Doug Axe at Cambridge University, and published in the peer-reviewed Journal of Molecular Biology, has shown that the number of functional amino acid sequences is tiny:

Doug Axe’s research likewise studies genes that it turns out show great evidence of design. Axe studied the sensitivities of protein function to mutations. In these “mutational sensitivity” tests, Dr. Axe mutated certain amino acids in various proteins, or studied the differences between similar proteins, to see how mutations or changes affected their ability to function properly. He found that protein function was highly sensitive to mutation, and that proteins are not very tolerant to changes in their amino acid sequences. In other words, when you mutate, tweak, or change these proteins slightly, they stopped working. In one of his papers, he thus concludes that “functional folds require highly extraordinary sequences,” and that functional protein folds “may be as low as 1 in 10^77.”

The problem of forming DNA by sequencing nucleotides faces similar difficulties. And remember, mutation and selection cannot explain the origin of the first sequence, because mutation and selection require replication, which does not exist until that first living cell is already in place.

But you can’t show that to your friends, you need to send them a video. And I have a video!

A video of Doug Axe explaining the calculation

Here’s a clip from Illustra Media’s new ID DVD “Darwin’s Dilemma”, which features Doug Axe and Stephen Meyer (both with Ph.Ds from Cambridge University).

I hope you all read Brian Auten’s review of Darwin’s Dilemma! It was awesome.

Related DVDs

Illustra also made two other great DVDs on intelligent design. The first two DVDs “Unlocking the Mystery of Life” and “The Privileged Planet” are must-buys, but you can watch them on youtube if you want, for free.

Here are the 2 playlists:

I also recommend Coldwater Media’s “Icons of Evolution”. All three of these are on sale from Amazon.com.

Related posts

Dr. George Yancey lectures on anti-Christian bias in academia, and beyond

My good friend Wes posted this 28-minute lecture.

If you watch 5 minutes, then you’ll definitely stay and watch the whole thing. It’s fascinating.

Details:

Join Dr. George Yancey in an in depth discussion of the bias taking place within academia against religion in general, but more specifically Christianity. Within the discussion Dr.Yancey uses brief explanations of his previous book, Compromising Scholarship and many other excerpts of his past research as well as his forthcoming research to give us a new viewpoint on academia and religion.

I found a quick description of Dr. Yancey’s work in this New York Times article from July 2011.

It says:

Republican scholars are more likely than Democrats to end up working outside academia,as documented by Daniel Klein, an economist at George Mason University. Dr. Klein, who calls himself a classical liberal (a k a libertarian), says that the university promotes groupthink because its system of “departmental majoritarianism” empowers the dominant faction to keep hiring like-minded colleagues. And when a faculty committee is looking to hire or award tenure, political ideology seems to make a difference, according to a “collegiality survey” conducted by George Yancey.

Dr. Yancey, a professor of sociology at the University of North Texas, asked more than 400 sociologists which nonacademic factors might influence their willingness to vote for hiring a new colleague. You might expect professors to at least claim to be immune to bias in academic hiring decisions.

But as Dr. Yancey reports in his new book, “Compromising Scholarship: Religious and Political Bias in American Higher Education,” more than a quarter of the sociologists said they would be swayed favorably toward a Democrat or an A.C.L.U. member and unfavorably toward a Republican. About 40 percent said they would be less inclined to vote for hiring someone who belonged to the National Rifle Association or who was an evangelical. Similar results were obtained in a subsequent survey of professors in other social sciences and the humanities.

Dr. Yancey, who describes himself as a political independent with traditional Christian beliefs and progressive social values, advises nonliberal graduate students to be discreet during job interviews. “The information in this research,” he wrote, “indicates that revealing one’s political and religious conservatism will, on average, negatively influence about half of the search committee one is attempting to impress.”

Dr. Yancey’s research was a survey, not a field experiment, so it’s impossible to know how many of those academics who confessed to hypothetical bias would let it sway an actual decision. Perhaps they’d try to behave as impartially as the directors of graduate studies in Dr. Gross’s experiment.

The lecture is a real eye-opener. It turns out that in academia, you are likely to be viewed the same way as blacks were viewed by slave-owners, and Jews were viewed by Nazis. Stereotypes, ignorance and hatred abound.

We have a lot of work to do to correct these perceptions, and unfortunately nothing that Christians see and hear in church is likely to change this. Until we get serious about prodding our young people to think and achieve, this is what people on the secular left will think of us. Not because they really are smarter, but because we are not capable of pointing out the nonsense on their side of the aisle, e.g. – eternal universes, aliens seeding the Earth with life, fatherlessness is good for children, and so on. If we don’t study the evidence, then their stupidity will rule the day, and they are the ones who are entrenched in academia.

Carson Weitnauer: putting atheism on the defensive

Here’s an article at Reasons for God that explains a few simple questions that you can ask your atheist friends.

He writes:

Though it has been persistently marketed to us as a worldview that stands for reason and science, the truth is that the atheistic worldview is riddled with contradictions and outlandish claims. And because most secular people haven’t studied why atheism is true, an excellent evangelistic strategy for you and your church is to understand these five challenges for atheism.

In my experience, it is only once people realize that their own worldview doesn’t work that they become interested in seeking something that does. While some would suggest you just have to wait for people to hit rock bottom, I think a more gracious and effective approach is to humbly challenge their pretense to have a sensible worldview.

By God’s grace, studying these five holes in the atheistic worldview can create a powerful opportunity for you and your church to share the wisdom and love of Jesus Christ.

[…]Because of their fundamental commitment to impersonal matter and laws, the atheist faces very difficult problems in at least five unique areas:

  • Consciousness
  • Free will
  • Purpose
  • Reason, including mathematics and science
  • Objective moral facts, including universal human rights and the reality of evil

Here’s my favorite of the 5:

Leading atheists such as Sam Harris dismiss free will as a matter of course. Or as Tom Clark at Naturalism.org puts it, “Judged from a scientific and logical perspective, the belief that we stand outside the causal web in any respect is an absurdity, the height of human egoism and exceptionalism.”

Dr. Angus Menuge, the current President of the Evangelical Philosophical Society, explains the problem: “before we can talk of being responsible for our decisions, we need an account of why those decisions belong to us. But the trouble is, on a naturalistic view, there is no entity that can plausibly own any mental states, there is simply a plurality of parallel, impersonal processes in the brain.”

The denial of free will logically leads to the denial of personal responsibility for any of our behaviors or beliefs. But if everything about “you” is determined, then “you” could not have reasonably chosen to believe what you do. If a-rational things and laws determined your neurological structure, “you” literally cannot make any decisions about what you believe or why you believe it.

This article is worth a look if you want to start a discussion with an atheist.