Tag Archives: Origin of Life

James Shapiro: an honest naturalist admired by ID supporters

As a pro-ID person, I am naturally suspicious of naturalistic scientists. They always say that material forces and chance can explain every single thing in nature, and there are no effects in nature that are best explained by an intelligence. Well, some in nature are best explained by unintelligent causes alone. But I think there are some effects in nature that are more like meaningful sentences or meaningful computer code – and that those are best explained as a result of an intelligence.

One effect in nature where that is clearly analogous to language/code is the biological information in proteins and in DNA. ID people keep telling naturalists that functional information in the first living cell cannot be generated by blind forces in the time available in Earth’s history. But naturalists always seem to diminish the problem and say that blind forces can create information. Well, most naturalists do.

Here’s one who doesn’t, though: James Shapiro. Dr. Shapiro is a microbiologist and a professor in the Department of Biochemistry and Molecular Biology at the University of Chicago. His undergraduate is from Harvard University.

He is very frank about how much naturalistic mechanisms can explain when it comes to the origin of life.

Excerpt: (links removed)

Around here we have a lot of respect for microbiologist James Shapiro, who had the guts and integrity to come over to ENV recently and spar over evolution with William Dembski, Doug Axe and Ann Gauger. Besides having a new book out that details his own dissatisfactions with conventional Darwinian evolutionary theory and that champions a provocative alternative view, Shapiro also blogs at the Huffington Post.

He continues to win our admiration, while evoking some poignancy as well.

In one post that got a fair amount of attention he had some sensible things to say to fellow evolutionists. Rather than hide behind “absolutist statements like ‘all the facts are on my side,'” as his University of Chicago colleague Jerry Coyne does, Shapiro advocates “active engagement” with Darwin critics. Enter into the controversy over evolution, he says, rather than pretend it doesn’t exist.

Perhaps even teach about it? Shapiro doesn’t go that far, but the permissibility of admitting the truth even to young people would seem to follow from his premise:

We need to demonstrate that evolution science is alive and well, as well as show how it is making remarkable progress through the application of molecular technologies — even though it does not have all the answers.

To the thoughtful scientist whose job is to uncover natural processes, this is surely a better way of advocating the scientific method than dogmatically asserting that we found all the scientific principles we need in centuries past.

Evolution supporters, he counsels, should admit they don’t have all the answers, including on a key question like the origin of life. In a remarkably candid statement, he writes:

In order to be truthful, we must acknowledge that certain questions, like the origins of the first living cells, currently have no credible scientific answer. However, given the historical record of science and technology in achieving the “impossible” (e.g., space flight, telecommunications, electronic computation and robotics), there is no reason to believe that unsolved problems will remain without naturalistic explanations indefinitely.

I don’t mind a naturalist who is honest about what we do and do not know.

More:

Surely there’s room to question Shapiro on why our ability to fly to the moon gives grounds for certainty that a purely “naturalistic” explanation of life’s origin will be forthcoming. Space flight is an accomplishment enacted in a material world but, more to the point, it’s a triumph of engineering — aka, intelligent design. It could not be accomplished at all without the direction of purposeful designers.

But note the implicit agreement with Stephen Meyer (Signature in the Cell: DNA and the Evidence for Intelligent Design): materialist explanations for “the origins of the first living cells” have, to date, indeed all miserably failed. In his book, Meyer shows how the evidence points persuasively to the action of some source of intelligent agency. Under the circumstances, if Shapiro is right, that would make intelligent design by default the lone viable theory of life’s origin.

Apart from gesturing to the advance of technology as a reason for keeping faith in naturalism, it would be interesting to know how Shapiro responds to Meyer’s case.

James Shapiro has debated with pro-ID people before. I have a set of audio cassettes from WAY WAY BACK which contains a debate between Robert Shapiro and Walter Bradley, whose lectures on the evidence for design in nature I have featured before. Although some naturalists like Richard Dawkins run away from debates, some, like Shapiro do not. And that’s good for science.

If you want to read a great book on what intelligent design is really about, you really need to read Signature in the Cell. This is the best on the argument for intelligent design in nature from the evidence of proteins and DNA. We are still waiting for a really great pro-ID book on the Cambrian explosion, the sudden origin of all major body plans 540 million years ago – but maybe Dr. Meyer is already working on that now, since he published a peer-reviewed paper on it in a science journal, a while back.

Stephen C. Meyer and Keith Fox debate intelligent design and evolution

From Justin Brierley’s “Unbelievable” podcast.

Details:

Stephen Meyer is a leading proponent of Intelligent Design who directs the Centre for Science and Culture at the Discovery Institute in Seattle. His most recent book “Signature in the Cell” claims to show that the DNA code is the product of intelligent mind, not naturalistic processes. Keith Fox is Professor of Biochemistry at Southampton University. He chairs the UK Christians in Science network but disagrees strongly with ID. They debate how life could have originated and whether design is allowed as an explanation in science.

The MP3 file is here.

Summary: (stuff in italics is my snarky paraphrase)

Meyer:

  • background and how he got interested in intelligent design
  • his research focus is on the origin of life – the first replicator
  • summarizes the history of origin of life studies
  • authored the book “Signature in the Cell”
  • the DNA enigma: where did the information in DNA come from?
  • naturalistic explanations of the DNA information have failed
  • but intelligent agents are known to be able to produce information
  • the best explanation of the information in DNA is that an intelligent agent authored it
  • Meyer’s book was named by atheist philosopher of science Thomas Nagel as a Times Literary Supplement Book of the Year in 2010
  • why is design so controversial? Many people think that Darwin explained why nature appears design
  • the Darwinian view is that nature can create the appearance of design using mutation and selection
  • however, Darwinian mechanisms cannot explain the origin of the first living cell, it assumes replication, and the origin of life is about where the first replicator comes from

Fox:

  • Meyer’s argument is not about the evolution of life after the first cell
  • Meyer’s case for design is about the origin of life
  • naturalists do not know a naturalistic explanation for the origin of life
  • there are a number of naturalistic hypotheses for the origin of life, like the RNA-first hypothesis
  • maybe in a few years one of them will turn out to be correct
  • what intelligent design is arguing from a gap in our current naturalistic knowledge to infer that God intervened in nature

Meyer:

  • that’s not what intelligent design is at all
  • the approach ID theorists use is the inference to best explanation
  • you evaluate all explanations, non-intelligent causes and intelligent causes
  • you prefer the best possible explanation
  • we know that minds are capable of producing information just like the information we find in DNA

Fox:

  • living cells replicate, so they have the ability to introduce mutations as they replicate and then some of those mutations can be selected
  • so maybe the process of replicating that living cells do created the first living cell
  • maybe the first living cell created itself, X brought X into being, self-creation, what’s irrational about that?

Meyer:

  • the issue is the origin of life – where did the first living cell come from?
  • you cannot appeal to the operations that a living cell can perform to explain the origin of the first living cell
  • there was no first living cell operating before the first living cell
  • there was no replication, mutation or selection before the first living cell
  • in fact, in my book I show that there is no known naturalistic mechanism that is able to produce the information needed for the first living cell
  • nothing can create itself, that is self-contradictory
Fox:
  • Well, you are just saying that because something is complex that God did it
Meyer:
  • Sadly, no. What I actually said needed to be explained was the information, not complexity
  • And we know from software engineering that the process of adding information to code is performed by programmers
  • in the absence of any adequate naturalistic explanation for information, we are justified in taking the explanation that we are familiar with – namely, intelligent agency – based on our uniform, universal experience of what causes information
Fox:
  • well, maybe we can appeal to the mutation and selection in existing living cells to explain the origin of the first living cell
  • maybe there were living cells before the first living cell, and then these other living cells created the first living cell
Meyer:
  • we can’t keep invoking mutation and selection when those processes are not operating prior to the origin of the first living cell
Fox:
  • well maybe some bare-bones self-replication molecule was a precursor to the first living cell
Meyer:
  • even to generate very limited replicator would require a large amount of information
  • the argument I am making is – where does the evolution come from?
Fox:
  • well, maybe we will think of an explanation for information that is naturalistic in 20 years
  • we’ve thought of explanations to things that were NOT information before
  • so maybe we will be able to think of something to explain information based on our ability to explain NOT information before

Moderator: Change topics: the Dover decision

Meyer:

  • the Discovery Institute opposed the policy that causes the trial
  • the wording of the statute was poor
  • the judge was completely wrong in his decision
  • young earth creationists used the phrase “intelligent design” to cover their agenda
  • intelligent design is an inference using the normal methods of science
Fox:
  • intelligent design is a science stopper because it stops looking for a naturalistic explanation
  • everything in nature must have a naturalistic explanation
  • everything has to be explained using matter and time and chance
  • it just has to be that way!!!!
Meyer:
  • well, what luck would you have explaining an effect like Mt. Rushmore?
  • can you explain that using matter,time and chance?
  • Mt. Rushmore was the product of intelligence, not wind and erosion
  • similarly, there is information in the cell, and we know that intelligence causes information
Fox:
  • So you are saying that we don’t understand and therefore an intelligence is necessary?

Meyer:

  • no I am saying we DO understand and we are making an inference based on that understanding
  • you are the one who is insisting on a material explanation because you pre-suppose materialism
  • we know that minds have causal powers, and we can infer mind as an explanation from information
Fox:
  • well nature is a seamless chain of material causes and effects
Meyer:
  • agents can act without violating the laws of nature
  • even humans can act as intelligent agents to create information in books, and they don’t violate the laws of nature
  • intelligent causes are real, and they explain effects in nature
Fox:
  • you’re trying to impose on science something to do with meaning and purpose
Meyer:
  • no that’s not what we’re doing, we’re inferring from from the fact that we ourselves are known causes of information to the fact that an intelligence cause is the best explanation for information in the cell
Fox:
  • but I am a materialist, I need a materialist explanation
Meyer:
  • mind IS an answer to the how question
  • we infer to mind in many other scientific disciplines, like cryptography, archaeology, etc.
  • a materialist might accuse an archaeologist of engaging in a “scribe-of-the-gaps” argument, but the best explanation of an artifact with information is a scribe
  • we are inferring that mind is the cause from the nature of the effect: information
Moderator: is it appropriate to call DNA “information”

Fox:

  • well DNA is just a molecular polymer, any reference to information is just by analogy
Meyer:
  • DNA is a molecular polymer, but it also exhibits the property of specified complexity
  • the arrangement of bases, which function as machine instructions in a software program, for performings task in the cell
  • we have observed that the property of specified complexity always comes from an intelligence
Fox:
  • well, maybe there are other sequences that would work, so maybe it’s really not uncommon to develop functioning sequences by chance alone, without an intelligence
Meyer:
  • you can measure how precise the functional specificity is in DNA and proteins

Moderator: is Shannon information the same as functional information

Meyer:

  • Shannon information refers to the sequences of digits or symbols that do not necessarily have any function, i.e. – a four character string QSZX has as much Shannon information as WORD. However, only the latter is functional against the pattern of the English language. There are arrangements of DNA bases and amino acids that have the same number of symbols/characters as a functional sequence would have, but they have no biological function – they do not exhibit specified complexity
Fox:
  • Well, maybe there are lots and lots of sequences of DNA and proteins so that it is fairly easy to get a functional one by chance

Meyer:

  • DNA sequences that are functional are extremely rare, protein sequences are even more rare
  • this is not my opinion, this is what the research shows – functional protein sequences are rare
Fox:
  • well maybe there are other functional sequences that are occur before the first functional sequence that are precursors to the first functional sequence
  • maybe there are billions of years of replication, mutation and selection before the first replication, mutation and selection

Meyer:

  • you can’t get to the first selectable functional sequence by appealing to precursor selectable functional sequences – there are no selectable functional sequences before the FIRST one
  • you have to get the first selectable functional sequence by chance alone, because there is nothing to mutate or select before the first replicator
  • the chance hypothesis has been rejected because the minimal amount of information for the simplest replicator is too high to get by chance alone, given the resources, including time, that are available

Moderator: Keith are you confident that naturalism will be able to substantiate these naturalism-of-the-gap speculations that you offer in response to Meyer’s actual science that we have today? 

Fox:

  • well, it is hard to know for sure because it was just a fluke event
  • but there’s nothing irrational or unscientific or miraculous about it – the fluke would have a material explanation
  • there is nothing that we can detect that would implicate God, my speculations about a fluke which I cannot observe or measure or test would all be compatible with an atheistic worldview that omits God as a causal entity

Meyer:

  • where are those material processes that could account for this fluke then?
  • the whole point of this argument is that the information in DNA transcends the material components in the sequence
  • it’s the arrangement of the material parts/letters/characters/symbols/instructions that needs to be explained
Fox:
  • Well, I just have a different philosophy of science that rules out intelligent causation a priori

Meyer:

  • Yes, that’s the difference between us – you pre-suppose that all explanations of natural phenomena must exclude intelligent causes

There is a bit more where Meyer talks about how parts of the cell are implementations of various design patterns (Gang of Four design patterns) that are used by software architects who design software.

Find more posts on Stephen C. Meyer here.

List of peer-reviewed papers supporting intelligent design now up to 50

Ann Gauger working away in her lab
Molecular biologist Ann Gauger working in her lab

From Evolution News.

Excerpt: (links removed)

While intelligent design research is a new scientific field, recent years have been a period of encouraging growth, producing a strong record of peer-reviewed scientific publications. New publications continue to appear, now listed at our updated page.

The current boom goes back to 2004, when Discovery Institute senior fellow Stephen Meyer published a groundbreaking paper advocating ID in the journal Proceedings of the Biological Society of Washington. There are multiple hubs of ID-related research.

Biologic Institute, led by molecular biologists Doug Axe and Ann Gauger, is “developing and testing the scientific case for intelligent design in biology.” Biologic conducts laboratory and theoretical research on the origin and role of information in biology, the fine-tuning of the universe for life, and methods of detecting design in nature. That’s Dr. Gauger at the Biologic lab pictured above.

Another ID research group is the Evolutionary Informatics Lab, founded by senior Discovery Institute fellow William Dembski along with Robert Marks, Distinguished Professor of Electrical and Computer Engineering at Baylor University. Their lab has attracted graduate-student researchers and published multiple peer-reviewed articles in technical science and engineering journals showing that computer programming “points to the need for an ultimate information source qua intelligent designer.”

Other pro-ID scientists around the world are publishing peer-reviewed pro-ID scientific papers. These include biologist Ralph Seelke at the University of Wisconsin Superior, Wolf-Ekkehard Lönnig who recently retired from the Max Planck Institute for Plant Breeding Research in Germany, and Lehigh University biochemist Michael Behe.

Researchers have published their work in a variety of relevant technical venues, including peer-reviewed scientific journals, peer-reviewed scientific books from mainstream university presses, trade-press books, peer-edited scientific anthologies, peer-edited scientific conference proceedings and peer-reviewed philosophy of science journals and books.

These papers have appeared in scientific journals such as Protein ScienceJournal of Molecular BiologyTheoretical Biology and Medical ModellingJournal of Advanced Computational Intelligence and Intelligent InformaticsQuarterly Review of BiologyCell Biology InternationalRivista di Biologia/Biology ForumPhysics of Life ReviewsAnnual Review of Genetics, and many others. At the same time, pro-ID scientists have presented their research at conferences worldwide in fields such as genetics, biochemistry, engineering, and computer science.

This body of research is converging on a consensus: complex biological features cannot arise by unguided Darwinian mechanisms, but require an intelligent cause.

My favorite area of ID research is the area of protein formation. I like to read about the research done by Doug Axe and Ann Gauger in that area. Research performed by Doug Axe at Cambridge University, and published in the peer-reviewed Journal of Molecular Biology, has shown that the number of functional amino acid sequences (ones that can form functioning proteins) is tiny:

Doug Axe’s research likewise studies genes that it turns out show great evidence of design. Axe studied the sensitivities of protein function to mutations. In these “mutational sensitivity” tests, Dr. Axe mutated certain amino acids in various proteins, or studied the differences between similar proteins, to see how mutations or changes affected their ability to function properly. He found that protein function was highly sensitive to mutation, and that proteins are not very tolerant to changes in their amino acid sequences. In other words, when you mutate, tweak, or change these proteins slightly, they stopped working. In one of his papers, he thus concludes that “functional folds require highly extraordinary sequences,” and that functional protein folds “may be as low as 1 in 10^77.”

The problem of forming DNA by sequencing nucleotides faces similar difficulties. And remember, mutation and selection cannot explain the origin of the first sequence, because mutation and selection require replication, which does not exist until that first living cell is already in place. I think that this very valuable research, indeed.

You can read more about the problem of protein synthesis in this previous post.