Tag Archives: Darwin

Ann Gauger’s new peer-reviewed paper on Darwinian evolution

Amazing new research paper by the Biologic Institute. The PDF of the paper, “Reductive Evolution Can Prevent Populations from Taking Simple Adaptive Paths to High Fitness,” is available here.

The MP3 file is here.

Participants

  • Jay Richards, Director of Research at the CRSC, (Discovery Institute)
  • Ann Gauger, senior research scientist at the Biologic Institute

About Ann:

Ann is a senior research scientist at Biologic Institute. Her work uses molecular genetics and genomic engineering to study the origin, organization and operation of metabolic pathways. She received a BS in biology from MIT, and a PhD in developmental biology from the University of Washington, where she studied cell adhesion molecules involved in Drosophila embryogenesis. As a post-doctoral fellow at Harvard she cloned and characterized the Drosophila kinesin light chain. Her research has been published in Nature, Development, and the Journal of Biological Chemistry.

Topics:

  • Co-authored with microbiologist Ralph Seelke at the University of Wisconsion
  • Purpose: study whether bacteria can evolve the ability to fix a broken protein (e.g. – enzyme)
  • Two areas are broken in the enzyme
  • If you fix the first one, it works a little but not fully (slight advantage)
  • If you fix the second one, it starts to work fully (huge advantage)
  • It’s a “two-step adaptive path” – a textbook case for evolution
  • should be able to hit both mutations and get back full functionality
  • At the start of the experiment, the cell is churning out broken protein
  • there is a cost to the cell for create the broken protein
  • the cell can either go through the adaptive path and repair the protein
  • OR, it can shut off production of the broken protein
  • EITHER PATH gives a selective advantage
  • So what happens? The cells NEVER followed the adaptive path
  • They almost ALWAYS turn off the production of the broken protein
  • It happens in 30-50 generations, in 14 different cultures
  • Each culture had a different way of turning off the production
  • They tested on 10^12 cells
  • Only one cell made the first repair, none made the second repair
  • It’s more advantageous to STOP PRODUCING the broken protein as soon as possible
  • The first cell that gets rid of the non-functional protein first overtakes the whole culture
  • so, even adaptive paths that provide a benefit with one mutation are unlikely to be followed
  • The point: even promising theoretical adaptive pathways MAY NOT WORK in experiments

I wrote about Doug Axe’s recent research paper here. He is the Director of the Biologic Institute.

Related posts

MUST-LISTEN: Audio of debate between Stephen Meyer and Peter Atkins

Justin Brierley has put together an amazingly high-quality debate. I made a rough transcript, so please see below for that.

The MP3 file is here. (60 minutes)

Details:

The documentary film “Expelled” is presented by US Actor Ben Stein and makes the case that scientists who question Darwinian orthodoxy and support Intelligent Design are being “expelled” from academia.

As the UK edition of the DVD is released we ask “Is freedom of thought at stake or is Intelligent Design out of bounds when it comes to biological science?”

Stephen C Meyer is co founder of the Discovery Institute in the USA and a major proponent of Intelligent Design.

Peter Atkins is Professor of Chemistry at Oxford University and an outspoken atheist.

They both feature in “Expelled” and join Justin to debate the pros and cons of Intelligent Design theory.

Mark Haville who is bringing the film to the UK also joins the discussion.

Meyer’s PhD is from Cambridge, and he has a wonderful new book called “Signature in the Cell”. He explains intelligent design for beginners here in his CNN editorial.

Other stuff

Learn more about intelligent design

My rough transcript of the Meyer-Atkins debate

Stephen Meyer:
– started researching on ID while doing his PhD at Cambridge
– the question is whether the information-bearing properties in DNA require a designer
– what cause is adequate to explain the digital code that in the simplest living cell
– alternative explanations like self-organization and RNA-first have failed
– so the best explanation for functional sequences of parts is an intelligent designer
– Darwinists have responded to this argument with insults and suppression of dissent

Peter Atkins:
– intelligent design is creationism
– there is no science at all in it
– information can emerge without an intelligent designer
– structures emerge spontaneously, no agent is needed to generate the structure
– information in DNA is also a structure

Stephen Meyer:
– structure and information are two different things
– many structures emerge spontaneously
– structure may be like the vortex that occurs when water goes down a drain

Peter Atkins:
– the vortex is information

Stephen Meyer:
– structures are different from functionally-specified digital information
– in DNA, there is a 4-digit alphabet that is used to create code sequences
– the thing to be explained is where do the functional sequences come from

Peter Atkins:
– information can grow without an agent
– the second law of thermodynamics
– the universe is falling into disorder
– but there are local abatements of chaos that create information
– evolution can cause the amount of information to grow

Stephen Meyer:
– that’s just an assertion
– I agree that energy flow through a system can produce spontaneous order
– but spontaneous order is not the same thing as information

Peter Atkins:
– spontaneous order is the same as information

Stephen Meyer:
– it’s not order that needs to be explained it’s specified complexity

Peter Atkins:
– what do you mean by specified complexity?

Stephen Meyer:
– the chemical bonds that connect to each letter do not determine the letter
– the chemical bonding sites will accept any letter as easily as any other
– any one of the 4 bases (letters) can attach at any place along the backbone

Peter Atkins:
– the selection of which letter comes next is determined by evolution

Stephen Meyer:
– that is just an assertion
– there is no physical process that sequences the letters to have a function

Peter Atkins:
– do you believe in evolution? YES OR NO!

Mark Haville:
– for him to answer the question you have to define the word
– do you mean macro or micro? biological or stellar? directed or undirected?

Peter Atkins:
– undirected molecules to man evolution by natural processes

Stephen Meyer:
– but even Dawkins doesn’t believe in evolution then
– you’re including the origin of life from non-living matter in evolution
– Dawkins says that there is no naturalistic explanation for that

Mark Haville:
– you need to define your terms

[They discuss of the movie Expelled and the case of Richard Sternberg]

Stephen Meyer:
– the problem is people don’t want to talk about the science
– they denounce dissent as unscientific
– they will not debate about whther natural causes can explain the information
– I want to talk about the science

Peter Atkins:
– ID people raise interesting questions for naturalists to work on
– but you want to tell us what the answer is (intelligence) before we begin
– you start from the idea that an intelligence was involved

Justin Brierley:
– but you start with the idea that natural mechanisms can explain everything!

Stephen Meyer:
– for Dr. Atkins, only explanations based on material processes are valid

Peter Atkins:
– that is correct

Stephen Meyer:
– but we think that the activities of mind can explain some effects
– e.g. – the best explanation of the Rosetta stone is a mind

Peter Atkins:
– but we naturalists think of minds as material as well

Stephen Meyer:
– that’s a materialist pre-supposition on your part
– we would have to have a debate about mind and body

Mark Haville:
– I think that the materialist position is socially dangerous
– the problem with naturalism is that it is an ideology
– the ideology pushes absurdities, e.g. – the universe came from nothing uncaused
– and naturalists exert power over others to force them to believe nonsense

Stephen Meyer:
– science progresses as the result of scientists disagreeing
– both sides agree to the facts
– the debate is about the interpretation of those facts
– and one side is being ruled out a priori based on the pre-supposition of materialism

Peter Atkins:
– why do you say that an intelligence is involved in DNA but not general relativity

Stephen Meyer:
– it is always logically possible that intelligence can be invlved in any effect
– the main thing is that explanations based on intelligence should not be ruled out

Peter Atkins:
= well you can’t appeal to any non-material process in expaining anything
– those are the rules

Moderator:
– what does intelligent design have to do with religion?

Stephen Meyer:
– creationism is about understanding the istory of life using the Bible
– intelligent design is about using the same method of inquiry as Darwin
– we know that information arises from intelligent causes
– humans create information all the time by using intelligence to sequence parts

Moderator:
– are intelligent design proponents disreputable?

Stephen Meyer:
– what’s disreputable is shutting down debate by setting arbitrary rules

Peter Atkins:
– we are both interested in the same questions

Moderator:
– why won’t you let Stephen publish his papers then?

Peter Atkins:
– because it breaks the pre-suppositions of naturalism and materialism

Stephen Meyer:
– you’re shutting down inquiry by using an arbitrary definition of science

Mark Haville:
– we need to define the word science
– science should be based on what we can observe empirically
– we can observe micro-evolution empirically
– but Darwinism goes beyond what is observable to postulate macro-evolution

Peter Atkins:
– but paleobiology is replete with evidence

Stephen Meyer:
– paleobiology uses a method of inference that I think is valid
– but intelligent design uses the same mode of reasoning which is also valid

Peter Atkins:
= you’re intellectually lazy
– we’re smart, we’re using our brains

Moderator:
– you’re saying that appeals to intelligent causes ends science?
– is ID the view that some things are too complex to be explained with naturalism?

Peter Atkins:
– yes, and to teach children that materialism is false is child abuse

Stephen Meyer:
– let’s drop the insults and the rhetoric and focus on the arguments
– the ID argument is not based on what we don’t know, it’s based on what we DO know
– first, we can ask what undirected natural processes can and cannot do
– second, we can ask what we know about intelligent causes from our own experience
– what we do know seems to me to require an intelligent agent as a cause

Peter Atkins:
– GOD! Do you mean God!? Do you mean God!?

Stephen Meyer:
– I personally mean God, but all that the arguments proves is a generic intelligent cause
– and I am using the same method of investigation that Darwin used to get there
– what we know from our experience is that a mind is needed to create information

Peter Atkins:
– NONSENSE! ABSOLUTE NONSENSE!

Stephen Meyer:
– in my book, I list 10 predictions made by ID, so it’s not a science-stopper
– furthermore, the enterprise of science began with th goal of understanding God
– consider the earliest scientists, people like James Boyler and Johannes Kepler

Peter Atkins:
– that was 300 years ago, we’ve moved on

Mark Haville:
– what about Max Planck then?

Stephen Meyer:
– how about James Clark Maxwell?

Mark Haville:
– we need to focus on the facts

Peter Atkins:
– what do you mean by the facts?

Mark Haville:
– well the fact is that Darwinism has no mechanism to produce new information

Peter Atkins:
– well copying errors introduces beneficial mutations

Stephen Meyer:
– let’s focus on where we get the first information from the simplest organism
– you can’t account for the first organism by appealing to copying errors
– to add functionality to a program, you need new lines codes from an intelligence
– once you have life, you can generate some new information
– but you can’t generate macro-evolution either

Peter Atkins:
– if we give you your explanation for teh origin of life, will you give this up

Stephen Meyer:
– of course! I’m a former theistic evolutionist
– but right now the evidence is not there for it
– we have to decide these questions based on what we see with our own eyes today

Peter Atkins:
– but I pre-suppose materialism as the starting point of all explanations
– you’re just intellectually lazy to abandon my pre-supposition

Stephen Meyer:
– why is it is less intellectually lazy to insist that materialism is true
– we are making plenty of predictions, and isn’t that what science is about?
– consider Junk DNA – you guys said it had no use
– now we know it has a use

Peter Atkins:
– naturalists were open to the idea that junk DNA might have a use before ID

Moderator:
– Dr. Meyer, what about the wall that locks out intelligence as an explanation?

Stephen Meyer:
– if these are interesting questions, then we should allow freedom of inquiry
– that’s how science advances

Peter Atkins:
– for all their science-talk really they are just saying God did it
– peope who don’t agree with me are not using their brains, like I do
– to give up on my pre-supposition of materialism is a denial of humanity

Mark Haville:
– there are important issues that are affected by our view of origins
– everyone who hasn’t seen Expelled movie should definitely see it

Was Nazi torturer Josef Mengele influenced by Christianity or Darwinism?

Story here from Evolution News.

Here is some of the evidence collected in the article.

In Mengele: The Complete Story, Gerald L. Posner and John Ware write:

Precisely what corrupted Mengele’s eager young mind is hard to pin down. Probably it was a combination of the political climate and that his real interest in genetics and evolution happened to coincide with the developing concept that some human beings afflicted by disorders were unfit to reproduce, even to live. Perhaps the real catalyst in this lethal brew was that Mengele, first at Munich and later at Frankfurt, studied under the leading exponents of this “unworthy life” theory. His consummate ambition was to succeed in this fashionable new field of evolutionary research.

[…]Medicine at German universities was in any case more complementary to Mengele’s real interest in evolution, since it was taught in accordance with the guidelines of the social Darwinist theory that Hitler and a growing number of German academics found so attractive.

[…]One of the earliest influence on the student doctor was Dr. Ernst Rudin, whose lectures Mengele regularly attended….Rudin was a leading proponent of the theory that doctors should destroy “life devoid of value.” Rudin himself was one of the architects of Hitler’s compulsory sterilization laws, which were enacted in July 1933.

Compulsory sterilization? That sounds like Obama’s science czar!

In Children of the Flames: Dr. Josef Mengele and the Untold Story of the Twins of Auschwitz, Lucette Matalon Lagnado and Sheila Cohn Dekel write:

The messianic quality of social Darwinism seems to have appealed to the young Mengele. His writings suggest that he was especially struck by their use of the phrase “the fate of mankind.” From his youthful encounter with their distorted ideals, to his old age, a weary and broken exile, Mengele would continue to feel a personal allegiance to the social Darwinists. At the university, the question of the “biological quality of mankind” may have been esoteric to most of Mengele’s classmates. But for him, it was apparently a clarion call.

Is it any wonder that the secular left is so interested in embryonic stem cell research, and cloning? They like scientific progress, and their worldview has no foundation for the right to life, or any objective human rights. They are thus rational in sacrificing the weak to make their own lives better.

Are all worldviews equal when it comes to morality?

Notice the difference between people influenced by Christianity, like William Wilberforce, and people influenced by Darwinism, like Josef Mengele. On the one worldview, you have man made in the image of God, for the purpose of having a relationship with God. And our job is to help them to have that relationship while respecting their free will (part of being made in the image of God means you have free will). And on the other worldview, you have survival of the fittest, the strong exterminating the weak to keep them from reproducing and wasting precious resources, so that the strong can pursue pleasure without being encumbered by the needs of others.

Here’s my previous post contrasting Wilberforce and Hitler, and another where I examine who is more responsible for the mass murders of the 20th century, and the millions of deaths caused by abortion, and environmentalist bans on DDT. My series of posts explaining why morality is not rational on atheism is here. Atheists may act better than their worldview allows, but that’s only because we are still living on the fumes of a dying Christian culture. If you want real atheist morality, unencumbered by Christianity, then just look at North Korea.

I’m going to be strict with comments again – please post your evidence along with your assertions. I cited evidence for my assertions.