Tag Archives: Evidence

News

Doug Axe explains the chances of getting a functional protein by chance

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I’ve talked about Doug Axe before when I described how to calculate the odds of getting functional proteins by chance.

Let’s calculate the odds of building a protein composed of a functional chain of 100 amino acids, by chance. (Think of a meaningful English sentence built with 100 scrabble letters, held together with glue)

Sub-problems:

  • BONDING: You need 99 peptide bonds between the 100 amino acids. The odds of getting a peptide bond is 50%. The probability of building a chain of one hundred amino acids in which all linkages involve peptide bonds is roughly (1/2)^99 or 1 chance in 10^30.
  • CHIRALITY: You need 100 left-handed amino acids. The odds of getting a left-handed amino acid is 50%. The probability of attaining at random only L–amino acids in a hypothetical peptide chain one hundred amino acids long is (1/2)^100 or again roughly 1 chance in 10^30.
  • SEQUENCE: You need to choose the correct amino acid for each of the 100 links. The odds of getting the right one are 1 in 20. Even if you allow for some variation, the odds of getting a functional sequence is (1/20)^100 or 1 in 10^65.

The final probability of getting a functional protein composed of 100 amino acids is 1 in 10^125. Even if you fill the universe with pre-biotic soup, and react amino acids at Planck time (very fast!) for 14 billion years, you are probably not going to get even 1 such protein. And you need at least 100 of them for minimal life functions, plus DNA and RNA.

Research performed by Doug Axe at Cambridge University, and published in the peer-reviewed Journal of Molecular Biology, has shown that the number of functional amino acid sequences is tiny:

Doug Axe’s research likewise studies genes that it turns out show great evidence of design. Axe studied the sensitivities of protein function to mutations. In these “mutational sensitivity” tests, Dr. Axe mutated certain amino acids in various proteins, or studied the differences between similar proteins, to see how mutations or changes affected their ability to function properly. He found that protein function was highly sensitive to mutation, and that proteins are not very tolerant to changes in their amino acid sequences. In other words, when you mutate, tweak, or change these proteins slightly, they stopped working. In one of his papers, he thus concludes that “functional folds require highly extraordinary sequences,” and that functional protein folds “may be as low as 1 in 10^77.”

The problem of forming DNA by sequencing nucleotides faces similar difficulties. And remember, mutation and selection cannot explain the origin of the first sequence, because mutation and selection require replication, which does not exist until that first living cell is already in place.

But you can’t show that to your friends, you need to send them a video. And I have a video!

A video of Doug Axe explaining the calculation

Here’s a clip from Illustra Media’s new ID DVD “Darwin’s Dilemma”, which features Doug Axe and Stephen Meyer (both with Ph.Ds from Cambridge University).

I hope you all read Brian Auten’s review of Darwin’s Dilemma! It was awesome.

Related DVDs

Illustra also made two other great DVDs on intelligent design. The first two DVDs “Unlocking the Mystery of Life” and “The Privileged Planet” are must-buys, but you can watch them on youtube if you want, for free.

Here are the 2 playlists:

I also recommend Coldwater Media’s “Icons of Evolution”. All three of these are on sale from Amazon.com.

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Commentary

Interview with Jim Spiegel on “The Making of an Atheist” book

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Interview here at the EPS blog.

Excerpt:

Why might there be a tendency among some Christian philosophical critiques of atheism (or any other worldview for that matter) to under-represent or downright avoid how the sinful tendencies of the human heart figure into the formation of a worldview?

One reason for avoidance of this issue might be a concern for decorum.  I suppose it could appear unseemly or offensive even to suggest, much less to present as a thesis of a book, that a person’s lack of belief in God is, at bottom, a form of rebellion.  And I must admit that at times I felt uncomfortable writing the book for this reason.  However, the fact that it is a clear biblical truth compelled me to write it anyway.  But I was careful to be as generous and winsome as I could manage, given the subject matter.

And:

How does one become “entrenched” in an atheist’s mindset?

In my book I expound on two aspects of this process, which explains something of the obstinacy of atheists.  There is a phenomenon that I call “paradigm-induced blindness,” where a person’s false worldview prevents them from seeing truths which would otherwise be obvious.  Additionally, a person’s sinful indulgences have a way of deadening their natural awareness of God or, as John Calvin calls it, the sensus divinitatis.  And the more this innate sense of the divine is squelched, the more resistant a person will be to evidence for God.

You say that right living contributes to the perseverance of faith. How is that perseverance related to Christian virtue and the “cognitive health” that it brings?

Just as sinful thoughts and behavior corrupt us cognitively and warp our perspective on the world, obedience and virtue benefit us cognitively in a number of ways.  Not only do we avoid the intellectual warping and deadening of the sensus divinitatis that sin causes, but Scripture also makes clear that God grants special insight and wisdom to those who obey him (cf. Ps. 19:7, Ps. 25:9; Pr. 1:4, Pr. 11:2).  So you might say that the life of Christian virtue enhances our ability to think and reason, especially about moral and spiritual matters.

I can hardly wait to read this book so that I can get some guidelines for dialoguing with atheists about how they formed their worldview. Is this really how atheists formed their view?

Podcasts

MUST-HEAR: Jennifer Roback Morse debates on marriage at Columbia University

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Cloning her would solve the marriage problem
Dr. J makes marriage interesting and fun!

Dr. Jennifer Roback Morse defends marriage at Columbia University in this short hour-long exchange. This is your chance to hear how anti-child advocates of same-sex marriage really are. And Dr. J links SSM to unilateral divorce at the end of the Q&A, too. Awesome! This debate really needed to go for twice the time, and I look forward to hearing MORE debates from Dr. J.

Details:

Columbia University’s Federalist Society hosts a debate between Dr J and Professor Katherine Franke based on the question “Is Marriage Equality Possible?”  About an hour of audio includes opening position (Dr J), arguments (Prof. Franke), and rebuttal (Dr J), as well as a brief question-and-answer period.

The MP3 file is here.

Dr. J’s opening speech (15 min.)

Two basic contentions:

  • 1) same-sex marriage is not the equivalent of traditional marriage
  • 2) if we legislate that they are equal, then we are really redefining marriage by changing the essential purpose of marriage

A case study from Ireland:

  • a known sperm donor for a lesbian couple was excluded from having a relationship with the child he conceived
  • after the child was born, the sperm donor wanted regular contact with the child, but the women opposed giving him access
  • same-sex marriage requires that courts are able to assign parental rights instead of having rights assigned biologically, as with traditional marriage
  • That is why SSM is different from TM

What is the purpose of marriage?

  • Marriage is about attaching mothers and fathers to children, and mothers and fathers to one another
  • Children are born helpless from two opposite-sex parents and they need parental guidance and care during development
  • In TM, there is no third party needed in order to have a child
  • In TM, the biological parents have rights and responsibilities for the child
  • TM is about providing the child with justice
  • Every child is entitled a relationship to both biological parents, and is entitled to care, protection and nourishment from both parents, and every child is entitled to a stable family environment
  • the problem is that children don’t have standing to sue for these rights in court
  • so the purpose of marriage is that we have a social construct to provide these rights to children naturally, without the state having to intervene

The purpose of marriage according to SSM?

  • In SSM, the essential child-centered  purpose marriage is replaced with new purposes like pooling resources and having same-sex couples recognized by society

SSM redefines marriage in four ways:

  • it diminishes the entitlement of children to a relationship with both biological parents
  • it diminishes the identification of parental roles with biology
  • it requires the state to determine parental relationships, instead of recognizing biological parents
  • it enshrines the idea that mothers and fathers are interchangeable, that children don’t really need mothers AND fathers

Dr. Franke’s opening speech (20 min.)

Hard cases make bad law 1: the presumption of paternity

  • consider the case where a mother is married and has an affair resulting in a child
  • the Supreme Court has ruled that the father of the child has no right of contact
  • this is a case where marriage gets in the way of biological parents having a relationship with the child
  • so it can be the case where marriage is in conflict with the relationships to biological parents

Hard cases make bad law 2: the purpose of marriage can be changed

  • marriages was used to keep peace between families and communities
  • marriage used to be about trading and trafficking of women
  • so the concern for offspring was not always the greatest concern

TM and SSM are both equally able to create stability for children:

  • same-sex unions are just as stable for children as TM marriages

Same-sex unions do provide justice for the child:

  • giving the adults in same-sex couples the social recognition that opposite sex married couples have is good for children

Children can sue in court

  • children can use guardians to sue their parents in court to get their rights

Opposing SSM is racism

  • opposing same-sex marriage is equivalent to racism
  • we could abolish marriage completely and let individuals form private contracts, then the state would really be neutral on marriage

Dr. J’s rebuttal speech (5 min.)

The state cannot be neutral on marriage

  • what the deinstutionalization of marriage means is that the private contracts are made by adults and children will have no consideration in those contracts

Regarding the adultery case

  • the presumption of paternity is there to protect the marriage
  • such borderline cases almost never happen with TM, whereas in SSM these third party problems occur in 100% of the cases

Children are not happy being separated from their biological parents

  • adults do not have a right to exclude a child’s biological parents from having a relationship with them, and children are often not happy being excluded from their biological parents

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