Monthly Archives: May 2013

Polemics

Doug Axe explains the chances of getting a functional protein by chance

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I’ve talked about Doug Axe before when I described how to calculate the odds of getting functional proteins by chance.

Let’s calculate the odds of building a protein composed of a functional chain of 100 amino acids, by chance. (Think of a meaningful English sentence built with 100 scrabble letters, held together with glue)

Sub-problems:

  • BONDING: You need 99 peptide bonds between the 100 amino acids. The odds of getting a peptide bond is 50%. The probability of building a chain of one hundred amino acids in which all linkages involve peptide bonds is roughly (1/2)^99 or 1 chance in 10^30.
  • CHIRALITY: You need 100 left-handed amino acids. The odds of getting a left-handed amino acid is 50%. The probability of attaining at random only L–amino acids in a hypothetical peptide chain one hundred amino acids long is (1/2)^100 or again roughly 1 chance in 10^30.
  • SEQUENCE: You need to choose the correct amino acid for each of the 100 links. The odds of getting the right one are 1 in 20. Even if you allow for some variation, the odds of getting a functional sequence is (1/20)^100 or 1 in 10^65.

The final probability of getting a functional protein composed of 100 amino acids is 1 in 10^125. Even if you fill the universe with pre-biotic soup, and react amino acids at Planck time (very fast!) for 14 billion years, you are probably not going to get even 1 such protein. And you need at least 100 of them for minimal life functions, plus DNA and RNA.

Research performed by Doug Axe at Cambridge University, and published in the peer-reviewed Journal of Molecular Biology, has shown that the number of functional amino acid sequences is tiny:

Doug Axe’s research likewise studies genes that it turns out show great evidence of design. Axe studied the sensitivities of protein function to mutations. In these “mutational sensitivity” tests, Dr. Axe mutated certain amino acids in various proteins, or studied the differences between similar proteins, to see how mutations or changes affected their ability to function properly. He found that protein function was highly sensitive to mutation, and that proteins are not very tolerant to changes in their amino acid sequences. In other words, when you mutate, tweak, or change these proteins slightly, they stopped working. In one of his papers, he thus concludes that “functional folds require highly extraordinary sequences,” and that functional protein folds “may be as low as 1 in 10^77.”

The problem of forming DNA by sequencing nucleotides faces similar difficulties. And remember, mutation and selection cannot explain the origin of the first sequence, because mutation and selection require replication, which does not exist until that first living cell is already in place.

But you can’t show that to your friends, you need to send them a video. And I have a video!

A video of Doug Axe explaining the calculation

Here’s a clip from Illustra Media’s new ID DVD “Darwin’s Dilemma”, which features Doug Axe and Stephen Meyer (both with Ph.Ds from Cambridge University).

I hope you all read Brian Auten’s review of Darwin’s Dilemma! It was awesome.

Related DVDs

Illustra also made two other great DVDs on intelligent design. The first two DVDs “Unlocking the Mystery of Life” and “The Privileged Planet” are must-buys, but you can watch them on youtube if you want, for free.

Here are the 2 playlists:

I also recommend Coldwater Media’s “Icons of Evolution”. All three of these are on sale from Amazon.com.

Related posts

News

Obama administration wins appeal to deport German homeschooling family

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From Breitbart News.

Excerpt:

The Sixth Circuit Court of Appeals has upheld the Obama administration’s denial of asylum granted to the Romeike family, who fled Germany over its strict anti-homeschooling laws.

In a press release Tuesday, Michael Farris, founder and chairman of the Home School Legal Defense Association (HSLDA), said, “We believe the Sixth Circuit is wrong and we will appeal their decision. America has room for this family and we will do everything we can to help them.”

The Romeikes fled Germany in 2008 when they were subjected to criminal prosecution for homeschooling, which is largely illegal in their country. In 2010, however, the family was granted asylum by Immigration Judge Lawrence O. Burman, whose decision was overturned by the Board of Immigration Appeals in 2012. A three-judge panel of the Sixth Circuit heard the Romeikes’ appeal on April 23rd and issued a unanimous decision against the family.

In its decision, the court said that the Romeikes had not made a sufficient case and that the United States has not opened its doors to every victim of unfair treatment.

While the court acknowledged that the U.S. Constitution recognizes the rights of parents to direct the education and upbringing of their children, it refused to concede that the threats of heavy fines or loss of custody of their children by German authorities if the Romeikes refused to send their children to government schools were enough to classify them as a persecuted group and warrant asylum in the United States.

HSLDA has obtained over 120,000 signatures on a White House petition to stop deportation of the Romeike family.

If you are a Muslim “refugee” from Chechnya, you can collect $100,000 in welfare and then blow up some of the people who worked to pay for that. But a German homeschooling family? They are disgusting evangelical Christians who believe in marriage and family. They have to go back to Germany and have their children taken away from them by the government.

News

Amy Hall: Will right and wrong always be obvious?

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Here’s a post from Amy Hall of Stand to Reason that will cause you to think.

She writes:

A person doesn’t have to know the Bible in order to know right and wrong, right? Well, yes and no. It all depends on what value system is being fed to that person by society. A society saturated in a Christian understanding of morality will reinforce that understanding, even among its atheists. A society without the background of Christianity behind it will enforce a different understanding of morality. Atheists have the mistaken idea that objective morality is simply obvious to everyone, but the truth is, it’s not. All one has to do is look back through history (and in other cultures today) to see that this is so. Our damaged consciences are malleable.

Is murdering your child right or wrong? Ask these mothers in India, where it’s commonplace in some areas to let your girl die if you prefer a boy. Ask pre-Christian cultures. This is why I think atheists are being far too hasty when they argue that Christianity is expendable—unnecessary for a good society. If we see atrocious moral crimes in cultures not influenced by Christianity, we have no reason to think our current standards will continue in a culture that rejects Christianity.

[…]As I’ve written before, intrinsic human value has to be taught. A society’s view of the human person and its value will affect what that society views as being moral: We are just animals. Imperfect animals aren’t worth the trouble. Therefore, there’s a case to be made for killing them rather than caring for them. That conclusion reasonably follows from the non-Christian premise. As Christianity fades in influence and a different view of the human person gains acceptance, don’t expect that our society will continue to recognize that conclusion to be immoral. At that point, people will still consider themselves to be perfectly moral…but only because they’re judging themselves by a different standard of morality.

It’s difficult for us to recognize the depth our depravity when “everyone else is doing it.” Ask Gosnell’s nurses.

I like this post because it connects an apologetic concern to real life. This concern about right and wrong isn’t merely theoretical. It’s practical.

Think about the abortion really means, in practice. Basically, you have two-grown ups who are engaging in a recreational activity. In the course of that activity, they create a new innocent life that is distinct from their lives. A new human genetic code. This new person is weaker than either of her two parents. And her life imposes certain obligations on them. She needs food, and safety, and care. Like a baby bird who has fallen out of her tree. But when there is no God, there is no purpose to putting your needs second, and someone else’s first. You could do it, if it makes you feel happy. But having to take care of a newborn doesn’t normally make people who are have risky recreational sex happy. After all, people who have recreational sex instead of procreative sex are looking for recreation not responsibility.

And so what do these powerful people do to the new life they have created? Do they let this new life impose obligations on them? Do they let this new life lower the amount of happiness they themselves will have? No. They kill it. For the strong to refrain from killing the weak when the weak impose obligations on them, there has to be a design for human nature that makes moral obligations and selflessness rational, instead of merely pleasurable. Because we all know that being saddled with a newborn baby is not fun. There has to be something more going on than the pursuit of pleasure if the baby is going to live.

Similarly with no-fault divorce and gay marriage. First, we enacted no-fault divorce, which weakened the stability of marriage so that many children now grow up fatherless.  No one is careful about marriage anymore in order to provide children with what they need. Instead, we just “marry for love” and then dissolve it when it doesn’t feel good anymore. Same-sex marriage is the same thing again. The voluntarily removal of the biological father or mother from a child’s life. And why? Because the needs of children don’t matter. They’re smaller than we are, so we don’t care about them.

Is there anything more going on in our society other than the seeking of pleasure? I think that the seeking of “happiness” instead of goodness is now the dominant view. No one wants to be responsible for anyone else. No one wants to be obligated to anyone else. We all seem to want to be free of feeling bad. If we do wrong, we don’t want to be judged or reminded about what we did. If we hurt someone else, then we don’t want to have to make restitution for what we did. We try to hand our children off to strangers so that we don’t have to teach them ourselves. We don’t want to learn anything that might make us feel obligated to do the right thing instead of what we feel like doing. Other people are  just there to give us pleasure. It’s sad.

All of these concepts had meaning in a Judeo-Christian society that encouraged marriage and families. But those days are drifting away. Once upon a time, we had a social consensus that what mattered was doing the right thing – what we were designed to do. And it was OK to not feel good and to not feel happy, if you were doing the right thing. Happiness wasn’t the main goal of life. Now things are different.