Tag Archives: Ralph Seelke

Ann Gauger’s new peer-reviewed paper on Darwinian evolution

Amazing new research paper by the Biologic Institute. The PDF of the paper, “Reductive Evolution Can Prevent Populations from Taking Simple Adaptive Paths to High Fitness,” is available here.

The MP3 file is here.

Participants

  • Jay Richards, Director of Research at the CRSC, (Discovery Institute)
  • Ann Gauger, senior research scientist at the Biologic Institute

About Ann:

Ann is a senior research scientist at Biologic Institute. Her work uses molecular genetics and genomic engineering to study the origin, organization and operation of metabolic pathways. She received a BS in biology from MIT, and a PhD in developmental biology from the University of Washington, where she studied cell adhesion molecules involved in Drosophila embryogenesis. As a post-doctoral fellow at Harvard she cloned and characterized the Drosophila kinesin light chain. Her research has been published in Nature, Development, and the Journal of Biological Chemistry.

Topics:

  • Co-authored with microbiologist Ralph Seelke at the University of Wisconsion
  • Purpose: study whether bacteria can evolve the ability to fix a broken protein (e.g. – enzyme)
  • Two areas are broken in the enzyme
  • If you fix the first one, it works a little but not fully (slight advantage)
  • If you fix the second one, it starts to work fully (huge advantage)
  • It’s a “two-step adaptive path” – a textbook case for evolution
  • should be able to hit both mutations and get back full functionality
  • At the start of the experiment, the cell is churning out broken protein
  • there is a cost to the cell for create the broken protein
  • the cell can either go through the adaptive path and repair the protein
  • OR, it can shut off production of the broken protein
  • EITHER PATH gives a selective advantage
  • So what happens? The cells NEVER followed the adaptive path
  • They almost ALWAYS turn off the production of the broken protein
  • It happens in 30-50 generations, in 14 different cultures
  • Each culture had a different way of turning off the production
  • They tested on 10^12 cells
  • Only one cell made the first repair, none made the second repair
  • It’s more advantageous to STOP PRODUCING the broken protein as soon as possible
  • The first cell that gets rid of the non-functional protein first overtakes the whole culture
  • so, even adaptive paths that provide a benefit with one mutation are unlikely to be followed
  • The point: even promising theoretical adaptive pathways MAY NOT WORK in experiments

I wrote about Doug Axe’s recent research paper here. He is the Director of the Biologic Institute.

Related posts

Split decision on Texas evolution standards favors academic freedom

Over at the Discovery Institute’s Evolution News blog, they recently reported that the Texas State Board of Education reached a split decision on the state standards for teaching evolution.

Evolution News says this in their post:

Kudos to the New York Times for filing a story on the actions of the Texas State Board of Education that actually describes what happened last week. Unlike much of the rest of the newsmedia, the Times doesn’t tell only half of what happened or play up the hysterics. The story’s even-handed title is telling: “Split Outcome in Texas Battle on Teaching of Evolution.”

The NYT article they mentioned explains the compromise reached by the Texas State Board of Education.

First, the bad news:

…the board voted to drop a 20-year-old mandate that science teachers explore with their students the “strengths and weaknesses” of all theories.

But the board also passed some good amendments, among them this one:

…one that would compel science teachers to instruct students about aspects of the fossil record that do not neatly fit with the idea of species’ gradually changing over time, like the relatively sudden appearance of some species and the fact that others seem to remain unchanged for millions of years.

Let me explain why this is a big win for ID. One of my previous employers was a major academic publishing company. By major, I mean my alma mater’s campus library featured academic publication databases that I helped to code. In this company, it was well known that California and Texas were the two most important states, because their textbook standards set the guidelines for the other states.

The NYT article explains:

Whatever the 15-member board decides then will have consequences far beyond Texas, since the state is one of the largest buyers of textbooks in the nation. The new standards will be in place for the next decade, starting in 2010, and will influence the writing of the next generation of biology texts, which the state will order this summer.

John G. West of the Discovery Institute evaluates the board’s decision as positive:

“They did something truly remarkable today,” John G. West of the Discovery Institute, a group that questions Darwinism, said in a statement. “They voted to require students to analyze and evaluate some of the most important and controversial aspects of modern evolutionary theory.”

I actually have podcasts for you of the testimonies of pro-ID scholars given to the Texas Board. If you want to learn how scientists argue for academic freedom on issues of origins, you should listen to these three 15-minute podcasts.

  1. My favorite ID scholar Stepen C. Meyer testified on the Cambrian explosion and the fossil record, (podcast, article). Meyer holds a Ph.D in the Philosophy of Science from Cambridge University. I once saw him explain biological information using colorful lock-blocks, live. (He stole them from his children). I often draw it up for my co-workers on a white board, just like he does!
  2. Microbiologist Ralph Seelke testified about how his lab research that shows clear limits on how far bacteria can evolve, (podcast, article). Seelke holds a Ph.D in Microbiology from the University of Minnesota and the Mayo Graduate School of Medicine. He is a Professor in the Department of Biology and Earth Sciences at the University of Wisconsin-Superior.
  3. Biochemist Charles Garner testified on the chirality problem in chemical evolution, (podcast, article). He also discussed the importance of not glossing over the weaknesses of scientific theories. Garner holds a Ph.D. in Organic Chemistry from University of Colorado, Boulder. Garner is now a Associate Professor in the Department of Chemistry & Biochemistry at Baylor University.

For those looking for a definition of what intelligent design is, look here. I highly recommend the work of Canadian journalist Denyse O’Leary, who is probably the foremost expert on why there is an ID controversy. Her main blog on ID is called Post-Darwinist.

As a supporter of academic freedom, I sent a donation to the Discovery Institute’s Center for Science and Culture yesterday. The CSC is currently offering a free book with donations received before February 28th, 2009. For my annual donation, I chose Stephen C. Meyer’s forthcoming book “Signature in the Cell: DNA and the Evidence for Intelligent Design“.

On another note, I am also excited about Jay Richards’ forthcoming book, “Money, Greed, and God: Why Capitalism Is the Solution and Not the Problem“. Jay did a great lecture on basic economics for Christians and another great lecture on what Christians should think about global warming. Maybe his employer, the Acton Institute, will give me a free book if I send them a donation?

UPDATE: Casey Luskin just posted audio of Stephen C. Meyer responding to questions after is presentation at the hearing.