Now, I’m not an expert in DNA sequencing similarities, here is paper from Nature which argued for more distance between human and chimp genomes than the 98% similarity commonly asserted by Darwinists.
A Nature paper from January, 2010 titled, “Chimpanzee and human Y chromosomes are remarkably divergent in structure and gene content,” found that Y chromosomes in humans and chimps “differ radically in sequence structure and gene content,” showing “extraordinary divergence” where “wholesale renovation is the paramount theme.” Of course, the paper attributes these dramatic genetic changes to “rapid evolution during the past 6 million years.”
One of the scientists behind the study was quoted in a Nature news article stating, “It looks like there’s been a dramatic renovation or reinvention of the Y chromosome in the chimpanzee and human lineages.” The news article states that “many of the stark changes between the chimp and human Y chromosomes are due to gene loss in the chimp and gene gain in the human” since “the chimp Y chromosome has only two-thirds as many distinct genes or gene families as the human Y chromosome and only 47% as many protein-coding elements as humans.” According to the news piece, “Even more striking than the gene loss is the rearrangement of large portions of the chromosome. More than 30% of the chimp Y chromosome lacks an alignable counterpart on the human Y chromosome, and vice versa, whereas this is true for less than 2% of the remainder of the genome.”
But not wishing to offend the “myth of 1%”, the Nature news article carefully adds, “The remainder of the chimp and human genomes are thought to differ in gene number by less than 1%.”
A more recent paper (PDF) from PNAS (edited by arch-evolutionist Francisco Ayala, no less) has more.
Here’s the abstract:
The rise of comparative genomics and related technologies has added important new dimensions to the study of human evolution. Our knowledge of the genes that underwent expression changes or were targets of positive selection in human evolution is rapidly increasing, as is our knowledge of gene duplications, translocations, and deletions. It is now clear that the genetic differences between humans and chimpanzees are far more extensive than previously thought; their genomes are not 98% or 99% identical. Despite the rapid growth in our understanding of the evolution of the human genome, our understanding of the relationship be-tween genetic changes and phenotypic changes is tenuous. This is true even for the most intensively studied gene, FOXP2, which underwent positive selection in the human terminal lineage and is thought to have played an important role in the evolution of human speech and language. In part, the difficulty of connecting genes to phenotypes reflects our generally poor knowledge of human phenotypic specializations, as well as the difficulty of interpreting the consequences of genetic changes in species that are not amenable to invasive research. On the positive side, investigations of FOXP2, along with genomewide surveys of gene-expression changes and selection-driven sequence changes, offer the opportunity for “phenotype discovery,” providing clues to human phenotypic specializations that were previously unsuspected. What is more, at least some of the specializations that have been proposed are amenable to testing with noninvasive experimental techniques appropriate for the study of humans and apes.
Again, I’m not sure what the exact numbers are, this is not my area, but I think it’s interesting. I know that ICR is doing some work on computing the average level of difference across both genomes.
How likely is it that you could swish together amino acids randomly and come up with a sequence that would fold up into a functional protein?
Evolution News reports on research performed by Doug Axe at Cambridge University, and published in the peer-reviewed Journal of Molecular Biology.
Excerpt:
Doug Axe’s research likewise studies genes that it turns out show great evidence of design. Axe studied the sensitivities of protein function to mutations. In these “mutational sensitivity” tests, Dr. Axe mutated certain amino acids in various proteins, or studied the differences between similar proteins, to see how mutations or changes affected their ability to function properly.10 He found that protein function was highly sensitive to mutation, and that proteins are not very tolerant to changes in their amino acid sequences. In other words, when you mutate, tweak, or change these proteins slightly, they stopped working. In one of his papers, he thus concludes that “functional folds require highly extraordinary sequences,” and that functional protein folds “may be as low as 1 in 10^77.”11 The extreme unlikelihood of finding functional proteins has important implications for intelligent design.
Just so you know, those footnotes say this:
[10.] Douglas D. Axe, “Estimating the Prevalence of Protein Sequences Adopting Functional Enzyme Folds,” Journal of Molecular Biology, 1-21 (2004); Douglas D. Axe, “Extreme Functional Sensitivity to Conservative Amino Acid Changes on Enzyme Exteriors,” Journal of Molecular Biology, Vol. 301:585-595 (2000).
[11.] Douglas D. Axe, “Estimating the Prevalence of Protein Sequences Adopting Functional Enzyme Folds,” Journal of Molecular Biology, 1-21 (2004).
And remember, you need a lot more than just 1 protein in order to create even the simplest living system. Can you generate that many proteins in the short time between when the Earth cools and the first living cells appear? Even if we spot the naturalist a prebiotic soup as big as the universe, and try to make sequences as fast as possible, it’s unlikely to generate even one protein in the time before first life appears.
Here’s Doug Axe to explain his research:
If you are building a protein for the FIRST TIME, you have to get it right all at once – not by building up to it gradually using supposed Darwinian mechanisms. That’s because there is no replication before you have the first replicator. The first replicator cannot rely on explanations that require replication to already be in place.
How do you present theism as a rational belief to a person who thinks that the progress of science has removed the need for God?
Canadian science writer Denyse O’Leary writes about the history of cosmology at Evolution News.
Excerpt:
What help has materialism been in understanding the universe’s beginnings?
Many in cosmology have never made any secret of their dislike of the Big Bang, the generally accepted start to our universe first suggested by Belgian priest Georges Lemaître (1894-1966).
On the face of it, that is odd. The theory accounts well enough for the evidence. Nothing ever completely accounts for all the evidence, of course, because evidence is always changing a bit. But the Big Bang has enabled accurate prediction.
In which case, its hostile reception might surprise you. British astronomer Fred Hoyle (1915-2001) gave the theory its name in one of his papers — as a joke. Another noted astronomer, Arthur Eddington (1882-1944), exclaimed in 1933, “I feel almost an indignation that anyone should believe in it — except myself.” Why? Because “The beginning seems to present insuperable difficulties unless we agree to look on it as frankly supernatural.”
One team of astrophysicists (1973) opined that it “involves a certain metaphysical aspect which may be either appealing or revolting.” Robert Jastrow (1925-2008), head of NASA’s Goddard Institute for Space Studies, initially remarked, “On both scientific and philosophical grounds, the concept of an eternal Universe seems more acceptable than the concept of a transient Universe that springs into being suddenly, and then fades slowly into darkness.” And Templeton Prize winner (2011) Martin Rees recalls his mentor Dennis Sciama’s dogged commitment to an eternal universe, no-Big Bang model:
For him, as for its inventors, it had a deep philosophical appeal — the universe existed, from everlasting to everlasting, in a uniquely self-consistent state. When conflicting evidence emerged, Sciama therefore sought a loophole (even an unlikely seeming one) rather as a defense lawyer clutches at any argument to rebut the prosecution case.
Evidence forced theorists to abandon their preferred eternal-universe model. From the mid 1940s, Hoyle attempted to disprove the theory he named. Until 1964, when his preferred theory, the Steady State, lost an evidence test.
Here is a quick summary of some of the experimental evidence that emerged in the last few decades that caused naturalists to abandon the eternal universe that they loved so much when they were younger.
The importance of having a narrative
Now I want to make a very, very important point about Christianity and the progress of science. And that point is that it is very important that Christians present the evidence in exactly the way that Denyse presented it in that article – in its historical context, featuring the conflict between naturalists and the experimental evidence.
All Christians should be familiar with the following basic pieces of evidence which fit the war between science and naturalism narrative:
The origin of the universe
The cosmic fine-tuning
The origin of life (biological information)
The sudden origin of the Cambrian phyla
The habitability/observability correlation
When you talk about these evidences as a Christian theist to non-Christians, you have to have cultivated a genuine interest in reconciling your beliefs with science. You have to accept that there are two books that reveal God’s character and attributes. The book of nature, and the book of Scripture. And you need to be flexible about getting these two books to fit together. The book of nature gives us natural theology (see Romans 1). It tells us that God is Creator and Designer. The book of Scripture tells us that God stepped into history as a man to save us by taking the punishment for our headlong rush away from God, which the Bible calls sin. Science is one way that humans can recover some of basic knowledge about God. Knowledge that is only possible because God created and designed the universe (and us) in such a way that we are capable of making discoveries, and that the universe is capable of being explored and understood.
It’s very important to present these five basic evidences to non-Christians in the historical context. And here is the story you must tell: “In the beginning, there was the naturalism, and the naturalism tried to argue from ignorance that God was not Creator and God was not Designer. And then came the science, and now people have to give up their naturalism in order to not be crazy and irrational”. That’s the narrative you use when talking to non-Christians about science.
In the beginning was the naturalism:
In pre-scientific times, atheists maintained that the universe was eternal
In pre-scientific times, atheists maintained that a life-permitting universe was as likely as a life-prohibiting universe
In pre-scientific times, atheists maintained that the cell was a simple blob of jello that could spontaneously emerge in some warm pond
In pre-scientific times, atheists maintained that the sudden origin of the Cambrian phyla would be explained by subsequent fossil discoveries
In pre-scientific times, atheists maintained that there was nothing special about our galaxy, solar system, planet or moon
But then science progressed by doing experiments and making observations:
Scientists discovered redshift and the cosmic microwave background radiation (evidence for a cosmic beginning) and more!
Scientists discovered the fine-tuning of gravity and of the cosmological constant and more!
Scientists discovered protein sequencing and exposed the myth of “junk DNA” and more!
Scientists discovered an even shorter Cambrian explosion period and the absence of precursor fossils and more!
Scientists discovered galactic habitable zones and circumstellar habitable zones and more!
And now rational people – people who want to have true beliefs about reality – need to abandon a false religion (naturalism).
Now naturally, science is in a state of flux and things change. But you have to look at the trend of discoveries, and those trends are clearly going against naturalism, and in favor of Christian theism. No one is arguing for a deductive proof here, we are simply looking at the evidence we have today and proportioning our belief to the concrete evidence we have today. People who are guided by reason should not seek to construct a worldview by leveraging speculations about future discoveries and mere possibilities. We should instead believe what is more probable than not. That’s what a rational seeker of truth ought to do. Proportion belief to probabilities based on current, concrete knowledge.
Atheism, as a worldview, is not rooted in an honest assessment about what science tells us about reality. Atheism is rooted in a religion: naturalism. And the troubling thing we learn from looking at the history of science is that this religion of naturalism is insulated from correction from the progress of science. Nothing that science reveals about nature seems to be able to put a dent in the religion of naturalism, at least for most atheists.
It falls to us Christian theists, then, to hold them accountable for their abuse and misrepresentation of science. And that means telling the story of the progress of science accurately, and accurately calling out the religion of naturalism for what it is – a religion rooted in blind faith and ignorance that has been repeatedly and convincingly falsified by the progress of science in the modern era.