Tag Archives: Reason

Doug Axe explains the chances of getting a functional protein by chance

I’ve talked about Doug Axe before when I described how to calculate the odds of getting functional proteins by chance.

Let’s calculate the odds of building a protein composed of a functional chain of 100 amino acids, by chance. (Think of a meaningful English sentence built with 100 scrabble letters, held together with glue)

Sub-problems:

  • BONDING: You need 99 peptide bonds between the 100 amino acids. The odds of getting a peptide bond is 50%. The probability of building a chain of one hundred amino acids in which all linkages involve peptide bonds is roughly (1/2)^99 or 1 chance in 10^30.
  • CHIRALITY: You need 100 left-handed amino acids. The odds of getting a left-handed amino acid is 50%. The probability of attaining at random only L–amino acids in a hypothetical peptide chain one hundred amino acids long is (1/2)^100 or again roughly 1 chance in 10^30.
  • SEQUENCE: You need to choose the correct amino acid for each of the 100 links. The odds of getting the right one are 1 in 20. Even if you allow for some variation, the odds of getting a functional sequence is (1/20)^100 or 1 in 10^65.

The final probability of getting a functional protein composed of 100 amino acids is 1 in 10^125. Even if you fill the universe with pre-biotic soup, and react amino acids at Planck time (very fast!) for 14 billion years, you are probably not going to get even 1 such protein. And you need at least 100 of them for minimal life functions, plus DNA and RNA.

Research performed by Doug Axe at Cambridge University, and published in the peer-reviewed Journal of Molecular Biology, has shown that the number of functional amino acid sequences is tiny:

Doug Axe’s research likewise studies genes that it turns out show great evidence of design. Axe studied the sensitivities of protein function to mutations. In these “mutational sensitivity” tests, Dr. Axe mutated certain amino acids in various proteins, or studied the differences between similar proteins, to see how mutations or changes affected their ability to function properly. He found that protein function was highly sensitive to mutation, and that proteins are not very tolerant to changes in their amino acid sequences. In other words, when you mutate, tweak, or change these proteins slightly, they stopped working. In one of his papers, he thus concludes that “functional folds require highly extraordinary sequences,” and that functional protein folds “may be as low as 1 in 10^77.”

The problem of forming DNA by sequencing nucleotides faces similar difficulties. And remember, mutation and selection cannot explain the origin of the first sequence, because mutation and selection require replication, which does not exist until that first living cell is already in place.

But you can’t show that to your friends, you need to send them a video. And I have a video!

A video of Doug Axe explaining the calculation

Here’s a clip from Illustra Media’s new ID DVD “Darwin’s Dilemma”, which features Doug Axe and Stephen Meyer (both with Ph.Ds from Cambridge University).

I hope you all read Brian Auten’s review of Darwin’s Dilemma! It was awesome.

Related DVDs

Illustra also made two other great DVDs on intelligent design. The first two DVDs “Unlocking the Mystery of Life” and “The Privileged Planet” are must-buys, but you can watch them on youtube if you want, for free.

Here are the 2 playlists:

I also recommend Coldwater Media’s “Icons of Evolution”. All three of these are on sale from Amazon.com.

Related posts

William Lane Craig asks: should Christians embrace postmodernism?

Here’s a short clip:

Dr. Craig thinks that Christianity does a lot better when it is commended to others using logic and evidence. He thinks that postmodernism undermines logic and evidence.

Sean McDowell has more on what this means for Christians:

In Postmodern Youth Ministry, for example, Tony Jones argues that postmodernity is the most important culture shift of the past 500 years, upending our theology, philosophy, epistemology (how we know things), and church practice. It is an “earthquake that has changed the landscape of academia and is currently rocking Western culture.” (p. 11). Thus, to be relevant in ministry today, according to Jones and other postmodernists, we must shed our modern tendencies and embrace the postmodern shift.

For the longest time I simply accepted that we inhabit a postmodern world and that we must completely transform our approach to ministry to be effective today. But that all changed when I had the opportunity of hearing philosopher William Lane Craig speak at an apologetics conference not too long ago. “This sort of [postmodern] thinking,” says Craig, “is guilty of a disastrous misdiagnosis of contemporary culture.” (“God is Not Dead Yet,” Christianity Today, July 2008, p. 26). He argues that the idea that we live in a postmodern world is a myth. This may strike you as awfully bold. How can he make such a claim?

For one thing, says Craig, postmodernism is unlivable and contradictory: “Nobody is a postmodernist when it comes to reading the labels on a medicine bottle versus a box of rat poison. If you’ve got a headache, you’d better believe that texts have objective meaning!” (Reasonable Faith, 2008, p. 18) Craig speaks to tens of thousands of (mostly non-Christian) college students around the world every year and his conclusion is that we live in a cultural milieu that is deeply modernist. Reason, logic, and evidence are as important today as ever (although he’s careful not to overstate their importance, too).

Postmodernism and Apologetics

But this is not all Craig has to say! In the introduction to Reasonable Faith, Craig provocatively claims, “Indeed, I think that getting people to believe that we live in a postmodern culture is one of the craftiest deceptions that Satan has yet devised” (p. 18). Accordingly, we ought to stop emphasizing argumentation and apologetics and just share our narrative. Craig develops this idea further:

And so Satan deceives us into voluntarily laying aside our best weapons of logic and evidence, thereby ensuring unawares modernism’s triumph over us. If we adopt this suicidal course of action, the consequences for the church in the next generation will be catastrophic. Christianity will be reduced to but another voice in a cacophony of competing voices, each sharing its own narrative and none commending itself as the objective truth about reality, while scientific naturalism shapes our culture’s view of how the world really is (p. 18-19).

In a personal email, Craig relayed to me that he believes postmodernism is largely being propagated in our church by misguided youth pastors. While he meant the comment more to elicit a smile than to be taken as a stab in the back, I can’t help but wonder if he is right.

If our culture were so profoundly postmodernist, why have the “New Atheists,” as Wired magazine dubbed them, been so influential? Popular writers such as Christopher Hitchens, Sam Harris, and Richard Dawkins have recently written bestselling books attacking the scientific, historic, and philosophical credibility of religion in general and Christianity in particular. Their writings have wreaked havoc on many unprepared Christians. If our culture were postmodern their challenges should have fallen on deaf ears.

This is my experience as well. When I was an undergraduate student, I attended IVCF and the woman running it (Jill) was a feminist who pushed postmodernism and feminism hard. Every week brought another testimony emphasizing love and forgiveness while minimizing or denying theology, science, history and logic. She turned down all the efforts of the men to bring in professors to speak about the cosmological argument or the resurrection, etc.. It was testimonies and prayer walks and praise hymns every week. When I questioned the people she chose to give their testimonies (mostly women), I found that none had any reasons for thinking that what they were talking about really was true. As a consequence of that, they were soft on doctrine – regularly throwing out Bible verses that did “resonate” with their “intuitions”. The same thing happened to me again with Campus Crusade as a graduate student. Personal testimonies of changed lives, divorced from any search for truth, every week.

One girl in particular that I knew at that time named Kerry was fond of bashing the laws of logic and the use of evidence. When I questioned her about it, she cited the influence of a charismatic youth pastor named Drew. A little more probing revealed that she denied the reality of Hell, and was a universalist. She eventually married a friend of mine and to this day has never read a single book on apologetics all the way through. Her beliefs are very much focused on the here and now, making friends and feeling good about herself. She never shook the habit of dismissing any argument, no matter how well-supported, that contradicted her intuitions.

Advice for Christians who discuss their faith with atheists… from an atheist

I spotted this post by Jeffery Jay Lowder on The Secular Outpost, and I think it’s good advice.

There are times where two people speak the same language, use the same words, and mean very different things by the same words. In conversations between Christians and atheists, “faith” is one such word. For many atheists, the word “faith” means, by default, belief without evidence or even belief against the evidence. In contrast, I doubt many Christians would accept that definition. For example, according to the NIV translation, Hebrews 11:1 states, “Now faith is confidence in what we hope for and assurance about what we do not see.”

Victor Reppert, at Dangerous Idea, writes this about the word “faith.”

Every time you use the word “faith” in a discussion with an atheist, they are going to declare victory. They will presume that you are believing for no reason, and that you are are admitting that the evidence is against you.

I think he is probably right. If Christians want to dialogue with atheists, I think Christians would be well served to speak the ‘language’ of atheists. The word “faith” simply has too much baggage associated with it; inserting that word into the conversation is likely to become a distraction from whatever point the Christian was probably trying to make. So if you’re a Christian talking with atheists, my advice is to temporarily delete the word “faith” from your vocabulary. Find some other way to make your point.

A better word to use is “trust”, and here’s Christian apologist Greg Koukl of Stand to Reason to make the same point:

Christian apologist Jonathan Morrow had a similar post on Think Christianly. (Mark well the part he put in bold)

Excerpt:

In today’s post I want to share a conversation I had with some of the sharp young men during lunch. It had to do with how we talk about Christianity with our friends, family, and coworkers. Most of the time, well meaning Christians talk about Christianity in the context of religion…not reality. Is that a problem? Yes, and here’s why. Religion is understood as a personal and private feeling that is not accessible by everyone else. You can’t question, challenge, or investigate it; you must simply be tolerant of it (and by tolerant, I am using the modern misunderstanding of tolerance which believes that all religious views are equally valid simply because a person sincerely believes them). That’s why having a conversation about Christianity as a religion is a dead end. It’s a non-starter.

That’s why I encouraged these students to talk about Christianity in the context of reality where terms like truth, knowledge, reason, and evidence apply. Any claim about reality is either true or false (it can’t be both). If Christianity is not the kind of thing that can be true or false…the battle has already been lost and the Gospel cannot be seriously considered. We need to talk about Christianity in the same way we talk about having a prescription filled at the pharmacy or receiving instruction from a Doctor.

In today’s society, religion is a fuzzy (i.e., socially constructed or psychologically projected) category that makes little difference in everyday life. But if Christianity is true, then it speaks to ALL of life. It makes a comprehensive claim on reality. Jesus didn’t intend to merely address two hours of our week. As Christians we need to have more conversations about reality and less about religion.

I’ve even written a post about the concept of faith that is presented in the Bible and the word faith has nothing to do with blind belief in the Bible – it’s always based on evidence, so that people can know for certain what the truth is. I highly recommend it for anyone who disagrees with Jeffery,Greg or Jonathan. When you’re talking about Christianity, you’re talking about what you know. You’re talking about the way the world is, for everyone. When you talk about your belief in God, you should say “trust”. You should not say “faith”.

Positive arguments for Christian theism