Tag Archives: Biochemistry

MUST-READ: Doug Axe defends intelligent design at science conference in Germany

Doug Axe got his Ph.D from Caltech and did post-doc research at Cambridge University, and published some of his findings in the peer-reviewed Journal of Molecular Biology. He was trying to see whether it is easy or hard to shuffle amino acids randomly in order to make functional proteins. Those JMB publications show that the number of functional amino acid sequences is tiny, compared to the number of possible sequences.

Doug Axe’s research likewise studies genes that it turns out show great evidence of design. Axe studied the sensitivities of protein function to mutations. In these “mutational sensitivity” tests, Dr. Axe mutated certain amino acids in various proteins, or studied the differences between similar proteins, to see how mutations or changes affected their ability to function properly. He found that protein function was highly sensitive to mutation, and that proteins are not very tolerant to changes in their amino acid sequences. In other words, when you mutate, tweak, or change these proteins slightly, they stopped working. In one of his papers, he thus concludes that “functional folds require highly extraordinary sequences,” and that functional protein folds “may be as low as 1 in 10^77.”

And now let’s see what he was up to in Stuttgart, Germany.

Story here from Evolution News.


While there have been many events to discuss intelligent design sponsored by the scientific establishment this year, few have dared to invite an actual design proponent.

But on the 150th anniversary of On the Origin of Species, Biologic Institute Director Douglas Axe was invited to the National Museum of Natural History in Stuttgart, Germany, for a panel discussion titled Design without a Designer? where “the ‘bold generation’ of young thinkers turned up in droves, listening intently as the discussion went well beyond its advertised ninety minutes.”

Here’s the official description of the event (in German), and a translated excerpt:

On the occasion of the 150th anniversary of the first publication of Darwin’s theory, this high-caliber panel discussion between evolutionists and Darwin critics will consider the question of whether the evolution of life on Earth is based solely on blind and unguided natural processes, or whether there is non-religiously based, verifiable evidence of meaningful and purposeful acts of creative intelligence in the natural world. This meeting at the Stuttgart Museum of Natural History aims to contribute constructively and with clarity and objectivity to this important debate. A public debate between evolutionary biologists and evolutionary critics at this high level is very rare in Germany, and therefore can be expected to be a very exciting evening.

You can read more at the Biologic Institute. They even have excerpts from Doug’s opening statement. It’s short and to the point.


William Dembski and Stephen Meyer have both framed the design argument in terms of functional information, meaning information that specifies a significant functional outcome.  Since this fits well with my own understanding, I offer the following three-statement summary of the design argument:

First: Living things contain within their genomes large amounts of functional information.

Second: The only cause known to be capable of generating large amounts of functional information is intelligence.

And third: It is therefore reasonable to infer that the functional information in living things must have an intelligent source.

Here we have not a pronouncement but an argument based on evidence and logic.  It is perfectly fair to argue against it, of course, but it is hardly fair to dismiss it as dogma.

I like this, because I am a software engineer. This is what we do.

Stephen Meyer is named Daniel of the Year for 2009 by World Magazine

Dr. Stephen C. Meyer
Dr. Stephen C. Meyer

There can be only one. (H/T Evolution News)


From his office Meyer has ventured forth to debate at least nine prominent Darwinians on CNN, NPR, FOX, the BBC, and other venues. In it he has written numerous newspaper and magazine columns in defense of Intelligent Design (ID), as well as an academic article that became notorious five years ago when Richard Sternberg, a Smithsonian-affiliated scientist, agreed to publish it in the peer-reviewed Proceedings of the Biological Society of Washington.

[…]When Meyer completed his dissertation, “Of Clues and Causes: A Methodological Interpretation of Origin of Life Studies,” the University of Cambridge in 1991 awarded him its prestigious Ph.D. Meyer, having proceeded through questioning and discernment stages, had to decide whether to enter the courage stage. Everyone knows that microevolution—change within species—occurs, but the critical issue is whether the descendants of dinosaurs become birds through natural selection. Denying macroevolution leaves scientists unprotected even at some Christian colleges.

[…]Courage becomes a determinant once we count the cost and see that it’s great. Meyer’s first inkling came when “talking about my ideas to people at Cambridge High Table settings, and getting that sudden social pall.” But the cost was and is more than conversational ease: San Francisco State University in 1992 expelled a professor, Dean Kenyon, who espoused ID, and other job losses have come since.

I met Dr. Meyer for the first time at the Baylor University conference on intelligent design in 2000. He comes across as extremely genuine and approachable. At other conferences, he even remembered my name! I still hold out hope of one day going for a PhD (I even came up with a great idea this week) and it’s largely because of authentic Christian scholars like Dr. Meyer who inspire me with a vision of what is possible.

Science Daily reports the biological functions supported by Junk DNA

Here’s the Science Daily article. (H/T Evolution News)


…during early development, the proteins required for cell division come from the mother. The researchers speculate that the heterochromatin of the male D. melanogaster‘s X chromosome has rapidly evolved, such that after mating, the machinery involved in DNA packaging from a D. simulans mother no longer recognizes the D. melanogaster father’s “junk” DNA, Ferree said.

Casey Luskin writes:

Basically, so-called “junk”-DNA is involved in helping to package chromosomes in the cell. If two species have different “junk” DNA, then this prevents the proteins in the egg from properly packaging the chromosomes donated by the sperm. The organism does not develop properly.

Good news for pro-ID guys like me!