Doctors have replaced the cancer-stricken windpipe of a patient with an organ made in a lab, a landmark achievement for regenerative medicine. The patient no longer has cancer and is expected to have a normal life expectancy, doctors said.
[…]The windpipe is a hollow tube, about 4.5 inches long, leading to the lungs. A key part of it is a scaffold—which functions like a skeleton for the organ—consisting of tissues such as cartilage and muscle. As a first step, a team led by Alexander Seifalian of University College London used plastic materials and nanotechnology to make an artificial version of the scaffold in the lab. It was closely modeled on the shape and size of the Eritrean man’s windpipe.
Meanwhile, researchers at Harvard Bioscience Inc. of Holliston, Mass., made a bioreactor, a shoe-box-size device similar to a spinning rotisserie machine. The artificial scaffold was placed on the bioreactor, and stem cells extracted from the patient’s bone marrow were dripped onto the revolving scaffold for two days.
With the patient on the surgery table, Dr. Macchiarini and colleagues then added chemicals to the stem cells, persuading them to differentiate into tissue—such as bony cells—that make up the windpipe.
About 48 hours after the transplant, imaging and other studies showed appropriate cells in the process of populating the artificial windpipe, which had begun to function like a natural one. There was no rejection by the patient’s immune system, because the cells used to seed the artificial windpipe came from the patient’s own body.
Another success for ethical adult stem cell research.
Researchers at the University of Minnesota used adult stem cells to create a living human heart that they hope will revolutionize transplants.
The breakthrough, said lead researcher Dr. Doris Taylor, could ultimately mean that “donated” hearts are no longer used in transplant operations, circumventing the ethical problems involved in organ donation and obviating the need for drugs to combat immune system rejection.
Dr. Taylor, director of the university’s Center for Cardiovascular Repair, is one of the world’s leaders in heart organ repair and regeneration and has said it is her goal to create a living heart that can be transplanted into a patient, entirely out of stem cells.
She presented her team’s findings at the American College of Cardiology’s annual conference in New Orleans.
“The hearts are growing, and we hope they will show signs of beating within the next weeks,” she told the Daily Mail. “There are many hurdles to overcome to generate a fully functioning heart, but my prediction is that it may one day be possible to grow entire organs for transplant.”
The breakthrough is a follow-up on work Dr. Taylor completed in 2008 in which her team used stem cells to rebuild the hearts of rats. They removed all the muscle cells in a rat heart, leaving just a “scaffold” of other tissues such as blood vessels and valves. This scaffold was then repopulated with stem cells, which took their cues from the scaffold tissue to regenerate healthy, functioning heart muscle.
Another scientific breakthrough for ethical adult stem cells.
“The Republican party has been overtaken by the zealots, by the extremists, by the radicals … and they don’t seem to like Ohio very much… And quite frankly they act like they don’t like America very much. They want to change our Constitution. They want to change Medicare. They want to change labor rights. They want to change this country in fundamental ways.”
Does Ted Strickland encourage businesses to remain in Ohio and hire workers in Ohio?
Let’s see:
Wow. 400,000 jobs lost in Ohio while Strickland was governor? He sounds as competent at encouraging job creation as his fellow Democrat Barack Obama.
In June of last year, Strickland upset pro-life Ohio residents by using his line-item veto to axe the section of the $1.3 billion funding bill banning state funds for cloning human beings.
Mike Gonidakis, the director of Ohio Right to Life, told LifeNews.com at the time, “By vetoing a ban on using taxpayer funds for human cloning, Ted Strickland has demonstrated that he supports treating human life as a commodity.”
“Most Ohioans don’t share Governor Strickland’s cavalier disregard for the value of human life and they should not be forced to pay for its creation, exploitation and destruction in cloning research,” Gonidakis said.
In March 2007, Strickland feuded with pro-life advocates over his budget proposal that eliminated the $500,000 the state normally spends annually on encouraging kids to practice abstinence.
The governor said he would not apply for any more federal funds for abstinence education for future budgets.
In February 2007, Strickland would not fight to save an Ohio law that protects women from the dangerous RU 486 abortion drug which has killed seven women in the United States and injured more than a thousand more. With little fanfare, Strickland quietly dropped a legal effort to salvage a law that puts safety limits on the drug.
The Ohio state legislature previously approved a bill to bring the use of the abortion pill in Ohio in line with Food and Drug Administration guidelines.
During his tenure in Congress, Strickland had a strong pro-abortion voting record while Kasich compiled a strongly pro-life record.
Ohio Right to Life today announced its endorsement of a slate of pro-life candidates seeking elected office statewide. The pro-life organization picked Rob Portman as its endorsed candidate for the U.S. Senate and named John Kasich as its endorsed candidate for governor.
[…]Marshal Pitchford, the chairman of the Ohio Right to Life Society Board of Trustees said the pro-life movement in Ohio “is fortunate to have experienced and highly qualified pro-life candidates seeking the state’s executive offices.”
“John Kasich had an outstanding pro-life voting record during his career in Congress,” he said. “His running mate, Mary Taylor, is an articulate advocate of the right to life movement. As Governor and Lt. Governor, they will reflect the common sense and common decency of the people of Ohio.”
And he’s also lousy on traditional marriage and the rights of children to be raised by a mother and a father. He was opposed to the Constitutional Amendment banning same-sex marriage, and opposed to banning gay adoption in D.C. He’s a left-wing radical on social issues. Just like Barack Obama.
n June of last year,Strickland upsetpro-life Ohio residents by using his line-item veto to axe the section of the $1.3 billion funding bill banning state funds for cloning human beings.
Mike Gonidakis, the director of Ohio Right to Life, told LifeNews.com at the time, “By vetoing a ban on using taxpayer funds for human cloning, Ted Strickland has demonstrated that he supports treating human life as a commodity.”
“Most Ohioans don’t share Governor Strickland’s cavalier disregard for the value of human life and they should not be forced to pay for its creation, exploitation and destruction in cloning research,” Gonidakis said.
In March 2007, Strickland feuded with pro-life advocates over his budget proposal that eliminated the $500,000 the state normally spends annually on encouraging kids to practice abstinence.
The governor said he would not apply for any more federal funds for abstinence education for future budgets.
In February 2007, Strickland would not fight to save an Ohio law that protects women from the dangerous RU 486 abortion drug which has killed seven women in the United States and injured more than a thousand more. With little fanfare, Stricklandquietly droppeda legal effort to salvage a law that puts safety limits on the drug.
The Ohio state legislature previously approved a bill to bring the use of the abortion pill in Ohio in line with Food and Drug Administration guidelines.
During his tenure in Congress, Strickland had a strong pro-abortion voting record while Kasich compiled a strongly pro-life record.