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News

Yale University computer science professor takes a look at protein formation probabilities

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When I was in graduate school, we studied a book called “Mirror Worlds”, authored by famous computer science professor David Gelernter at Yale University. This week, I noticed that Dr. Gelernter had written an article in the prestigious Claremont Review of Books. In his article, he applies his knowledge of computer science to the problem of the origin of life.

Evolution, if it is going to work at all, has to explain the problem of how the basic building blocks of life – proteins – can emerge from non-living matter. It turns out that the problem of the origin of life is essentially a problem of information – of code. If the components of proteins are ordered properly, then the sequence folds up into a protein that has biological function. If the sequence is not good, then just like computer code, it won’t run.

Here’s Dr. Gelernter to explain:

How to make proteins is our first question. Proteins are chains: linear sequences of atom-groups, each bonded to the next. A protein molecule is based on a chain of amino acids; 150 elements is a “modest-sized” chain; the average is 250. Each link is chosen, ordinarily, from one of 20 amino acids. A chain of amino acids is a polypeptide—“peptide” being the type of chemical bond that joins one amino acid to the next. But this chain is only the starting point: chemical forces among the links make parts of the chain twist themselves into helices; others straighten out, and then, sometimes, jackknife repeatedly, like a carpenter’s rule, into flat sheets. Then the whole assemblage folds itself up like a complex sheet of origami paper. And the actual 3-D shape of the resulting molecule is (as I have said) important.

Imagine a 150-element protein as a chain of 150 beads, each bead chosen from 20 varieties. But: only certain chains will work. Only certain bead combinations will form themselves into stable, useful, well-shaped proteins.

So how hard is it to build a useful, well-shaped protein? Can you throw a bunch of amino acids together and assume that you will get something good? Or must you choose each element of the chain with painstaking care? It happens to be very hard to choose the right beads.

Gelernter decides to spot the Darwinist a random sequence of 150 elements. Now the task the Darwinist is to use random mutation to arrive at a sequence of 150 links that has biological function.

[W]hat are the chances that a random 150-link sequence will create such a protein? Nonsense sequences are essentially random. Mutations are random. Make random changes to a random sequence and you get another random sequence. So, close your eyes, make 150 random choices from your 20 bead boxes and string up your beads in the order in which you chose them. What are the odds that you will come up with a useful new protein?

[…]The total count of possible 150-link chains, where each link is chosen separately from 20 amino acids, is 20150. In other words, many. 20150 roughly equals 10195, and there are only 1080 atoms in the universe.

What proportion of these many polypeptides are useful proteins? Douglas Axe did a series of experiments to estimate how many 150-long chains are capable of stable folds—of reaching the final step in the protein-creation process (the folding) and of holding their shapes long enough to be useful. (Axe is a distinguished biologist with five-star breeding: he was a graduate student at Caltech, then joined the Centre for Protein Engineering at Cambridge. The biologists whose work Meyer discusses are mainly first-rate Establishment scientists.) He estimated that, of all 150-link amino acid sequences, 1 in 1074 will be capable of folding into a stable protein. To say that your chances are 1 in 1074 is no different, in practice, from saying that they are zero. It’s not surprising that your chances of hitting a stable protein that performs some useful function, and might therefore play a part in evolution, are even smaller. Axe puts them at 1 in 1077.

In other words: immense is so big, and tiny is so small, that neo-Darwinian evolution is—so far—a dead loss. Try to mutate your way from 150 links of gibberish to a working, useful protein and you are guaranteed to fail. Try it with ten mutations, a thousand, a million—you fail. The odds bury you. It can’t be done.

Keep in mind that you need many, many proteins in order to have even a simple living cell. (And that’s not even considering the problem of organizing the proteins into a system).

So, if you’re a naturalist, then your only resources to explain the origin of life are chance and mutation. As Dr. Gelernter shows, naturalistic explanations won’t work to solve even part of the problem. Not even with a long period of time.  Not even if you use the entire universe as one big primordial soup, and keep trying sequences for the history of the universe. It just isn’t possible to arrive at sequences that have biological function in the time available, using the resources available. The only viable explanation is that there is a computer scientist who wrote the code without using trial and error. Something that ordinary software engineers like myself and Dr. Gelernter do all the time. We know what kind of cause is adequate to explain functioning code.

News

Big wins for conservatives in Florida: education policy and right to life

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One area where the secular left is running unopposed is in the education system. Most states haven’t done a good job of pushing back against the education bureaucrats and the powerful, corrupt teacher unions. It’s so bad, that the schools can just go to law enforcement and have any parents who disagree with them persecuted for “domestic terrorism”. Who will stand up to them?

Here’s an article from the Daily Signal:

The Florida Department of Education rejected the original AP course standards for the black studies course under the state’s Stop WOKE Act, citing a lack of educational value and historical accuracy.

“As presented, the content of this course is inexplicably contrary to Florida law and significantly lacks educational value,” the Department of Education’s rejection letter said. “In the future, should [the] College Board be willing to come back to the table with lawful, historically accurate content, [the education agency] will always be willing to reopen the discussion.”

To draw attention to the issue and not simply capitulate to the College Board cartel, which holds a practical monopoly on Advanced Placement testing, is exactly the kind of tactic that needs to be used to loosen the far Left’s ascendent institutional strength.

In this case, Florida put a halt to ideological quackery masquerading as “history” being force-fed to aspiring college students.

The article goes into details about the woke, far-left content in the course, but you can imagine what the education system produces. The key point is that Ron DeSantis

That was not the only good news I found coming out of Florida.

Here’s another article from Daily Signal:

Florida’s state Supreme Court on Monday denied Planned Parenthood’s emergency motion to block the state’s 15-week abortion ban.

“As [Florida Gov. Ron DeSantis] said, we are better when everybody counts,” the governor’s press secretary, Bryan Griffin, said in a statement Tuesday, adding:

The Florida Supreme Court denied both of Planned Parenthood’s emergency motions asking the court to block Florida’s law from taking effect. The court also accepted jurisdiction of the case and set a briefing schedule. From here, we will continue to defend our pro-life protections.

House Bill 5, which took effect on July 1, bans abortion after 15 weeks of gestation. It allows exceptions when the mother’s life is at risk or in danger of “irreversible physical impairment,” or if the baby has a fetal abnormality, but does not offer exceptions for rape or incest.

“House Bill 5 protects babies in the womb who have beating hearts, who can move, who can taste, who can see, and who can feel pain,” DeSantis said when he signed the bill in April. “Life is a sacred gift worthy of our protection, and I am proud to sign this great piece of legislation, which represents the most significant protections for life in the state’s modern history.”

I took a quick look at who has appointed the judges on the Florida Supreme Court, and DeSantis has appointed 4 out of 7. What kind of judges would he appoint to the US Supreme Court? The same kind he appointed to the Florida Supreme Court. Appointing conservatives to the courts is something we know that DeSantis can do, because we have seen him do it. Don’t believe anyone’s words, believe their actions.

Here is my concern about elections. People think that their job is to wait until the campaigns start, watch the television ads, and then decide how they feel about the candidates. But this is a stupid way to choose a candidate. The right way to choose a candidate is the same way you choose any other employee – you look at their past employers, their past achievements, and call those employers and check references. If DeSantis gets elected as president, then I expect him to continue the battles that he’s already started as governor.

News

Alexander Vilenkin: “All the evidence we have says that the universe had a beginning”

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I’ve decided to explain why physicists believe that there was a creation event in this post. That is to say, I’ve decided to let famous cosmologist Alexander Vilenkin do it.

From Uncommon Descent.

Excerpt:

Did the cosmos have a beginning? The Big Bang theory seems to suggest it did, but in recent decades, cosmologists have concocted elaborate theories – for example, an eternally inflating universe or a cyclic universe – which claim to avoid the need for a beginning of the cosmos. Now it appears that the universe really had a beginning after all, even if it wasn’t necessarily the Big Bang.

At a meeting of scientists – titled “State of the Universe” – convened last week at Cambridge University to honor Stephen Hawking’s 70th birthday, cosmologist Alexander Vilenkin of Tufts University in Boston presented evidence that the universe is not eternal after all, leaving scientists at a loss to explain how the cosmos got started without a supernatural creator. The meeting was reported in New Scientist magazine (Why physicists can’t avoid a creation event, 11 January 2012).

[…]In his presentation, Professor Vilenkin discussed three theories which claim to avoid the need for a beginning of the cosmos.

The three theories are chaotic inflationary model, the oscillating model and quantum gravity model. Regular readers will know that those have all been addressed in William Lane Craig’s peer-reviewed paper that evaluates alternatives to the standard Big Bang cosmology.

But let’s see what Vilenkin said.

More:

One popular theory is eternal inflation. Most readers will be familiar with the theory of inflation, which says that the universe increased in volume by a factor of at least 10^78 in its very early stages (from 10^−36 seconds after the Big Bang to sometime between 10^−33 and 10^−32 seconds), before settling into the slower rate of expansion that we see today. The theory of eternal inflation goes further, and holds that the universe is constantly giving birth to smaller “bubble” universes within an ever-expanding multiverse. Each bubble universe undergoes its own initial period of inflation. In some versions of the theory, the bubbles go both backwards and forwards in time, allowing the possibility of an infinite past. Trouble is, the value of one particular cosmic parameter rules out that possibility:

But in 2003, a team including Vilenkin and Guth considered what eternal inflation would mean for the Hubble constant, which describes mathematically the expansion of the universe. They found that the equations didn’t work (Physical Review Letters, DOI: 10.1103/physrevlett.90.151301). “You can’t construct a space-time with this property,” says Vilenkin. It turns out that the constant has a lower limit that prevents inflation in both time directions. “It can’t possibly be eternal in the past,” says Vilenkin. “There must be some kind of boundary.”

A second option explored by Vilenkin was that of a cyclic universe, where the universe goes through an infinite series of big bangs and crunches, with no specific beginning. It was even claimed that a cyclic universe could explain the low observed value of the cosmological constant. But as Vilenkin found, there’s a problem if you look at the disorder in the universe:

Disorder increases with time. So following each cycle, the universe must get more and more disordered. But if there has already been an infinite number of cycles, the universe we inhabit now should be in a state of maximum disorder. Such a universe would be uniformly lukewarm and featureless, and definitely lacking such complicated beings as stars, planets and physicists – nothing like the one we see around us.

One way around that is to propose that the universe just gets bigger with every cycle. Then the amount of disorder per volume doesn’t increase, so needn’t reach the maximum. But Vilenkin found that this scenario falls prey to the same mathematical argument as eternal inflation: if your universe keeps getting bigger, it must have started somewhere.

However, Vilenkin’s options were not exhausted yet. There was another possibility: that the universe had sprung from an eternal cosmic egg:

Vilenkin’s final strike is an attack on a third, lesser-known proposal that the cosmos existed eternally in a static state called the cosmic egg. This finally “cracked” to create the big bang, leading to the expanding universe we see today. Late last year Vilenkin and graduate student Audrey Mithani showed that the egg could not have existed forever after all, as quantum instabilities would force it to collapse after a finite amount of time (arxiv.org/abs/1110.4096). If it cracked instead, leading to the big bang, then this must have happened before it collapsed – and therefore also after a finite amount of time.

“This is also not a good candidate for a beginningless universe,” Vilenkin concludes.

So at the end of the day, what is Vilenkin’s verdict?

“All the evidence we have says that the universe had a beginning.”

This is consistent with the Borde-Guth-Vilenkin Theorem, which I blogged about before, and which William Lane Craig leveraged to his advantage in his debate with Peter Millican.

The Borde-Guth-Vilenkin (BGV) proof shows that every universe that expands must have a space-time boundary in the past. That means that no expanding universe, no matter what the model, can be eternal into the past. No one denies the expansion of space in our universe, and so we are left with a cosmic beginning. Even speculative alternative cosmologies do not escape the need for a beginning.

Conclusion

If the universe came into being out of nothing, which seems to be the case from science, then the universe has a cause. Things do not pop into being, uncaused, out of nothing. The cause of the universe must be transcendent and supernatural. It must be uncaused, because there cannot be an infinite regress of causes. It must be eternal, because it created time. It must be non-physical, because it created space. There are only two possibilities for such a cause. It could be an abstract object or an agent. Abstract objects cannot cause effects. Therefore, the cause is an agent.

Now, let’s have a discussion about this science in our churches, and see if we can’t train Christians to engage with non-Christians about the evidence so that everyone accepts what science tells us about the origin of the universe.