Tag Archives: Stem Cell Research

Round up of articles on adult stem-cell research from FRC

I found these on their blog.

Adult Stem Cells–Saving Legs, Saving Lives

Excerpt:

Previous stories focused on the science of treating peripheral artery disease with adult stem cells. Often overlooked are the people whose lives have been changed or even saved by adult stem cell treatments.

Helen Thomas, 80, of Hastings, Michigan is one of those people. Helen’s painful circulatory problem in her leg meant she had trouble walking, rarely left home, and was facing amputation of her leg. But her physician, Kenneth Merriman of Hastings, asked around at a medical conference and found Dr. Randall Franz, who was doing a clinical trial at Grant Medical Center in Columbus, Ohio. Franz injected Helen’s own adult stem cells into her leg, causing new blood vessels to grow. Helen is now up and about, back to normal.

A Neurological Save with Adult Stem Cells

Excerpt:

When she was 30, Jennifer Osman was diagnosed with chronic inflammatory demyelinating polyneuropathy (CIDP), a neurological disorder that attacks the peripheral nervous system, progressively weakening and numbing its victim.

[…]Then Jennifer signed up for an adult stem cell study run by Dr. Richard Burt, chief of the Division of Immunotherapy at Northwestern University Feinberg School of Medicine. Her adult stem cells were collected and she received chemotherapy to knock out the rogue immune cells attacking her nervous system. Shortly after, on April 1, 2005, Jennifer received a transplant of her own adult stem cells and her immune system, now rebooted, began to rebuild itself. The process was slow and grueling, but she has taken no medication for the disease since 2008. Today, almost five years since her transplant, she is nearly symptom-free.

You Call That “Success”?

Excerpt:

A news story out yesterday exemplifies the “successes” of embryonic stem cells. The story proclaimed that scientists had “successfully used mouse embryonic stem cells to replace diseased retinal cells and restore sight in a mouse model of retinitis pigmentosa.” Sounds pretty good? Later there is the requisite hyperbole about treatments, that “Once the complication issues are addressed” and a list of retinal diseases that will be treated with embryonic stem cells.

Seeing Real Success with Adult Stem Cells

Excerpt:

In a paper published February 15, 2010, Oregon scientists showed that they could use bone marrow-derived adult stem cells to treat a rat model of retinitis pigmentosa. Visual function was significantly preserved in this study. An added benefit was that the cells could be easily grown in culture and administered intravenously; once injected, they traveled to the retina where they exerted their protective effect. The study highlights the possibility of using a patient’s own adult stem cells for treatment of retinitis, diabetic retinopathy, and macular degeneration.

A study by Canadian and Japanese researchers used human retinal stem cells that had been modified to increase their differentiation potential. When injected into the eyes of mice, the adult stem cells survived and differentiated into photoreceptors. Injected into a mutant mouse strain that lacks functional photoreceptors, the adult stem cells significantly improved visual function. The study was published online in the journal Stem Cells December 11, 2009.

Something to think about when the topic of embryonic stem cells comes up.

A social conservative’s evaluation of Tuesday’s election results

New York

First, social conservatives lost the special election in New York’s 23rd district.

Excerpt:

Doug Hoffman, the upstart third-party Conservative candidate for the special election in New York’s 23rd congressional district, conceded defeat to Democrat Bill Owens early Wednesday morning.

The final tally showed Owens beating out Hoffman by 4,000 votes, 49 percent to 45 percent. On social issues, Owens has identified himself as “pro-choice” regarding abortion, but on marriage, he indicated that he favored President Obama’s position: against same-sex “marriage,” but for civil unions.

[…]While polls on the eve of election-day showed Hoffman having pulled ahead by at least five points, Scozzafava’s weekend endorsement of Owens after the implosion of her own campaign, which had the blessing of national GOP leaders, may have proved the game-changer.

Scozzafava has close ties to the labor unions – her husband is a labor organizer – and channeled that on-the-ground support into Owens campaign. The Albany Times Union reports that powerful New York unions poured in hundreds of thousands of dollars to oppose Hoffman.

That’s a lost seat in the House of Representatives. And labor unions opposed the socially conservative candidate.

Maine

Next, social conservatives won against same-sex marriage in Maine.

Excerpt:

Maine voters handed traditional marriage supporters a major victory Tuesday night after rejecting a same-sex “marriage” law that the state government approved six months ago.

Though signed by Democratic Gov. John Baldacci, the law never went into effect, and remained in limbo after the success of the ballot initiative calling for a people’s vote.

Had the law been upheld, Maine would have been the sixth U.S. state to allow homosexual “marriage,” after Iowa, Connecticut, Vermont, New Hampshire and Massachusetts.

As of early Wednesday, the law was defeated 53% to 47%, despite polling data leading up to the vote showing the race in a dead heat.

[…]Same-sex “marriage” has now lost in all 31 states in which the question has been put to a popular vote.

Traditional marriage is the view that children should be raised by their own mother and father in a stable marriage. Same-sex marriage denies that children should have a right to be raised by a mother and father biologically related to them. See my previous post to understand why people oppose same-sex marriage. And here’s my case for the pro-life position.

Virginia

Social conservatives were elected as governor, lieutenant-governor and attorney general in Virginia.

Excerpt:

Virginia’s state elections saw a sweep for pro-life candidates into the state’s highest offices. Pro-life Republicans captured the offices of governor, lieutenant governor, and attorney general by wide margins.

Pro-life Republican Bob McDonnell handily beat his pro-abortion Democratic opponent Creigh Deeds. Election night returns showed McDonnell cruising to victory, garnering 59 percent of the vote to Deeds’ 41 percent with 99 percent of precincts reporting in.

[…]Pro-life Lt. Gov. Bill Bolling, a Republican, also handily won re-election with 57 percent of the vote, to 43 percent for his pro-abortion Democratic challenger Jody Wagner, with 99 percent of precincts reporting.

[…]Pro-life Republican Ken Cuccinelli also beat out his Democratic and pro-abortion challenger Steve Shannon for the office of attorney general, 58 percent to 42 percent with 99 percent of precincts reporting.

[…]”The Virginia Society for Human Life looks forward to working with all three of these stalwart pro-life leaders, as well as pro-life members of the State Senate and House of Delegates, to enact laws that will safeguard the right to life of unborn children and support their mothers, and protect older people and those with disabilities from denial of lifesaving medical treatment, food and water.”

Great news for social conservatives.

New Jersey

A pro-life, pro-family Republican was elected as governor of the strong Democrat state of New Jersey.

Excerpt:

Incumbent Democrat Gov. Jon Corzine conceded defeat last night to pro-life, pro-family Republican Chris Christie in New Jersey’s governor’s race.

Christie fought a hard-won battle against the incumbent Corzine and third-party candidate Chris Daggett, winning 49 percent of the vote. Corzine, whose bid for re-election received huge assistance from President Barack Obama, who personally campaigned for him in New Jersey, came in second with 45 percent of the vote, with Daggett trailing in third with six percent.

resident Obama had attempted to rally support behind Corzine by tapping into the popularity that garnered the President 57 percent of the vote in New Jersey in 2008. However neither Obama’s personal charisma, nor Corzine’s outspending Christie by almost 3-1 – $30 million to $11.5 million – could save the incumbent governor from defeat in an election that mainly turned on the economy and job stagnation, crippling fees and taxes (especially sky-high property taxes), and fiscal irresponsibility in Trenton that has run rampant during Corzine’s tenure.

[…]During the brutal campaign fight, Corzine, who was endorsed by abortion-provider Planned Parenthood, had attacked Christie in ads for the latter’s support of a constitutional amendment banning abortion and his opposition to embryonic stem-cell research.

Corzine is a big proponent of embryonic stem-cell research. However, New Jersey voters, frustrated with the state’s failure to close a $3 billion budget gap, rejected in November 2007 a $450 million ballot initiative to support a project that would have funded embryonic stem-cell research facilities. The setback was a political humiliation for Corzine, who had broken ground for the Christopher Reed Pavilion in October with the words “to the future,” only to have the voters shelve the project a month later.

Christie, on the other hand, received a critical endorsement from New Jersey’s foremost pro-life GOP Congressman Chris Smith. The pro-life leader’s approval for Christie, who admitted at the beginning of his campaign that he used to describe himself as “pro-choice” until the birth of his own children led him to embrace the pro-life position, was followed by the endorsement of New Jersey Right to Life.

[…]Both of Christie’s challengers, Corzine and Daggett, indicated that they would sign a bill legalizing same-sex “marriage” if given the opportunity.

So again, Barack Obama campaigned on behalf of the anti-life, anti-marriage Democrat candidate, but the Republican pro-life, pro-marriage candidate won the election. Social conservatism is as real to me as fiscal conservatism or foreign policy conservatism, so I am overjoyed that social conservatives won elected offices in 3 out of 4 states that voted for Obama, who is anti-life and anti-family.

Ethically-sound adult stem cell research cures paralysis in human patients

There are two kinds of stem-cell research. The first kind is called embryonic stem-cell research (ESCR). This kind is opposed by pro-lifers because it kills unborn persons by extracting their stem cells for use in medical research. The second kind is called adult stem-cell research (ASCR). This kind is supported by pro-lifers.

You may be surprised to know that ESCR doesn’t work as nearly as well as ASCR. Despite all the advocacy from left-wing Hollywood actors, ESCR has not helped a single patient. But ASCR in being used for 73 different kinds of therapies, and it keeps getting better and better. Here’s the latest scientific discovery in ASCR.

Story from Wayne State University, which made the discovery. (H/T Secondhand Smoke via ECM)

Excerpt:

A new study by a Wayne State University School of Medicine researcher details the outcome of adult stem cell grafts in spinal cord injuries and how the procedure led to increased mobility and quality of life for patients.

Associate Professor Jean Peduzzi-Nelson of the Department of Anatomy and Cell Biology conducted the study, “Olfactory Mucosal Autografts and Rehabilitation for Chronic Traumatic Spinal Cord Injury,” which was published online in the journal Neurorehabilitation and Neural Repair.

The process involves the use of adult stem-like progenitor cells in the patient’s own nasal tissue. The use of a person’s own stem cells, Peduzzi-Nelson said, lessens the problems of rejection, tumor formation and disease transmission.

In the study, 20 patients with severe chronic spinal cord injuries received a treatment combination of partial scar removal, transplantation of nasal tissue containing stem cells to the site of the spinal cord injury and rehabilitation. All of the patients had total paralysis below the level of their spinal cord injury before the treatment.

More here.

Wesley J. Smith notes that ASCR is getting more and more efficient:

A team led by scientists from The Scripps Research Institute has developed a method that dramatically improves the efficiency of creating stem cells from human adult tissue, without the use of embryonic cells. The research makes great strides in addressing a major practical challenge in the development of stem-cell-based medicine…

The new technique, which uses three small drug-like chemicals, is 200 times more efficient and twice as fast as conventional methods for transforming adult human cells into stem cells (in this case called “induced pluripotent stem cells” or “iPS cells”). “Both in terms of speed and efficiency, we achieved major improvements over conventional conditions,” said Scripps Research Associate Professor Sheng Ding, Ph.D., who led the study. “This is the first example in human cells of how reprogramming speed can be accelerated. I believe that the field will quickly adopt this method, accelerating iPS cell research significantly.”

See below for other breakthroughs in ASCR, as well as the political implications.

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