Tag Archives: Mutation

Casey Luskin and Stephen C. Meyer discuss the design inference

This episode of ID the Future is 17 minutes long. It’s the third in a series – here are parts one and two.

Details:

On this episode of ID the Future, Casey Luskin and Stephen Meyer finish up their talk with a discussion of why intelligent design presents the best explanation for the Cambrian explosion.

Special limited time offer: Save 43% and get 4 free digital books when you pre-order Darwin’s Doubt.

You can grab the MP3 here.

Topics:

  •  What sort of reasoning did Darwin use in The Origin of Species?
  • Can this method of “inference to the best explanation” be applied to the Cambrian explosion
  • The importance of appealing to causes that we have experienced ourselves
  • Example: explaining from an effect (volcanic ash) to a cause that his adequate (volcanic eruption)
  • We have experience of how volcanoes cause the ash, so we should infer based on what we know
  • In the case where the effect is information in biology, we see that naturalistic mechanisms are inadequate
  • But we know from our own experience that intelligent agents can generate information
  • Many people think that science must confine itself to materialistic explanations
  • If so, then it is possible miss out on the true explanation by ruling it out before looking at evidence

If you haven’t yet read Meyer’s first book, “Signature in the Cell”, you should probably grab that one. It’s the best book on intelligent design that’s out right now. It talks about the origin of the first living cell, surveying all naturalistic explanations for it, and concluding that the best explanation – the one most consistent with what we know now – is intelligent design.

Casey Luskin and Stephen C. Meyer discuss information outside the genome

This episode of ID the Future is 20 minutes long and it’s a follow up to a previous podcast I posted.

Details:

On this episode of ID the Future, hear the second part of Casey Luskin’s interview with Dr. Stephen C. Meyer, author of the forthcoming book Darwin’s Doubt: The Explosive Origin of Animal Life and the Case for Intelligent Design. Dr. Meyer discusses how the origin of information in the Cambrian explosion poses a problem for evolutionary biology.

Special limited time offer: Save 43% and get 4 free digital books when you pre-order Darwin’s Doubt.

You can grab the MP3 here.

Topics:

  • Last time, they discussed how the sudden origin of animal body plans requires an infusion of new information
  • Also, the sudden origin of animal forms is inexplicable naturalistically, because there are no transitional forms
  • New body plans require new genetic information
  • The Cambrian explosion involve a sudden increase of body plans, which means a sudden increase of information
  • For example, a new body plan requires dozens of new cell types
  • Each cell type will be composed of new proteins and enzymes
  • Proteins are composed of functional sequences of amino acids – genetic information
  • Can the neo-Darwinian mechanisms generate new functional sequences?
  • The problem with making functional sequences by chance: Product Rule
  • When calculating probabilities of forming a functional sequence, you multiply to calculate probabilities
  • A bike lock with 4 dials and 10 possibilities has 10 x 10 x 10 x 10 = 10,000 possibilities
  • Each sequence is equally likely to get by random guesses
  • But it’s far more likely that any random attempt will NOT work
  • Getting one or two settings right has no value to opening the lock, and will not be saved for later attempts
  • There is no credit for partial success: you have to get the whole combination right the first time
  • In addition, there are other sources of information other than DNA that are required for new body plans
  • For example, there is information in cell membranes, cytoskeletons, etc. which is also needed
  • Neo-Darwinism can only work on mutating genes – even in the best case it would just give you new proteins
  • Neo-Darwinism cannot add information in non-genome areas, which are required for new animal forms
  • The information in these non-genome areas are required to arrange the proteins to make new body pans
  • Genetic inofrmation = information in the genome, Epigenetic information = information outside the genome
  • This problem of information outside the genome is called “the problem of the origin of form”

So those last few points are, I think, a sneak peek into the contents of the new “Darwin’s Doubt” book.

If you haven’t yet read Meyer’s first book, “Signature in the Cell”, you should probably grab that one. It’s the best book on intelligent design that’s out right now. It talks about the origin of the first living cell, surveying all naturalistic explanations for it, and concluding that the best explanation – the one most consistent with what we know now – is intelligent design.

Can Darwinian evolution create new functional biological information?

Here’s a great article from Evolution News that explains the trouble that Darwinian evolution has in building up to functional new biological information by using a process of random mutation and natural selection.

Casey Luskin takes a look at a peer-reviewed paper that claims that Darwinian evolution can do the job of creating new information, then he explains what’s wrong with the paper.

Excerpt:

In Wilf and Ewens’s evolutionary scheme there is a smooth fitness function. Under this view, there is no epistasis, where one mutation can effectively interact with another to affect (whether positively or negatively) fitness. As a result, any mutations that move the search toward its “target” are assumed to provide an immediate and irrevocable advantage, and are thus highly likely to become fixed. Ewert et al. compare the model to playing Wheel of Fortune:

The evolutionary model that Wilf and Ewens have chosen is similar to the problem of guessing letters in a word or phrase, as on the television game show Wheel of Fortune. They specify a phrase 20,000 letters long, with each letter in the phrase corresponding to a gene locus that can be transformed from its initial “primitive” state to a more advanced state. Finding the correct letter for a particular position in the target phrase roughly corresponds to finding a beneficial mutation in the corresponding gene. During each round of mutation all positions in the phrase are subject to mutation, and the results are selected based on whether the individual positions match the final target phrase. Those that match are preserved for the next round. … After each round, all “advanced” alleles in the population are treated as fixed, and therefore preserved in the next round. Evolution to the fully “advanced” state is complete when all 20,000 positions match the target phrase.

The problem with this approach is that a string of biological information that has only some letters that are part of a useful sequence has no present function, and therefore cannot survive and reproduce.

Look:

Thus, Wilf and Ewens ignore the problem of non-functional intermediates. They assume that all intermediate stages will be functional, or lead to some functional advantage. But is this how all fitness functions look? Not necessarily. It’s well known that in many instances, no benefit is derived until multiple mutations are present all at once. In such a case, there’s no evolutionary advantage until multiple mutations are present. The “correct” mutations might occur in parallel, but the odds of this happening are extremely low. Ewert et al. illustrate this problem in the model by using the example of the difficulty of one phrase evolving into another:

Suppose it would be beneficial for the phrase

“all_the_world_is_a_stage___”

to evolve into the phrase

“methinks_it_is_like_a_weasel.”

What phrase do we get if we simply alternate letters from the two phrases?

“mlt_ihk__otli__siaesaaw_a_e_.”

Under the assumptions in the Wilf and Ewens model, the “fitness” of this nonsense phrase ought to be exactly half-way between the fitnesses of “all the world is a stage” and “methinks it is like a weasel.” Such a result only makes sense if we are measuring the fitness of the current phrase by its proximity to the target phrase.

But the gibberish of the intermediate phrase doesn’t cause any problem under Wilf and Ewens’s model. Not unlikeRichard Dawkins, they assume that intermediate stages will always yield some functional advantage. And as more and more characters in the phrase match the target, it becomes more and more fit. This yields a nice, smooth fitness function — rich in active information — not truly a blind search.

Not only is there that first problem, but here’s a second:

Wilf and Ewens endowed their mathematical model of evolution with foresight. It is directed toward a target — an advantage that natural selection conspicuously lacks. And what, in our experience, is the only known cause that is goal-directed and has foresight? It’s intelligence. This means that once again, the Evolutionary Informatics Lab has shown that simulations of evolution seem to work only because they’ve been intelligently designed.

This is worth the read. If Darwinian mechanisms really could generate code, then there would be no software engineers. The truth is, the mechanisms don’t work to create new information. For that, you need an intelligent designer.