This is from the Intelligent Design FAQ at the Discovery Institute. (H/T Justin Taylor tweet)

Here are the 5 points:

1. Genetics: Mutations cause harm and do not build complexity.
2. Biochemistry: Unguided and random processes cannot produce cellular complexity.
3. Paleontology: The fossil record lacks intermediate fossils.
4. Taxonomy: Biologists have failed to construct Darwin’s “Tree of Life.”
5. Chemistry: The chemical origin of life remains an unsolved mystery.

Let’s look at the first one:

Mutations cause harm and do not build complexity.

Darwinian evolution relies on random mutations that are selected by a blind, unguided process of natural selection that has no goals.  Such a random and undirected process tends to harm organisms and does not improve them or build complexity.  As National Academy of Sciences biologist Lynn Margulis has said, “new mutations don’t create new species; they create offspring that are impaired.” Similarly, past president of the French Academy of Sciences, Pierre-Paul Grasse, contended that “[m]utations have a very limited ‘constructive capacity’” because “[n]o matter how numerous they may be, mutations do not produce any kind of evolution.”

It’s a nice little overview, and all the sections are short like that – it’s just an introduction to each area.

There are lot more questions answered in the FAQ. It’s a good resource.