Tag Archives: Treatment

Adult stem cells therapy can fix a broken heart?

Mary sent me this article from the Irish Times.

Excerpt:

A new US study in which patients had their hearts repaired with stem cells has brought regenerative treatments for heart attacks a step closer.

The therapy, reported today in the Lancet  medical journal, halved the extent of normally permanent scarring on the heart, and led to the growth of new heart muscle.

However, the treatment produced no significant change in “ejection fraction” – a measure of the heart’s pumping capacity.

The Caduceus trial recruited a total of 25 patients with an average age of 53 who had all suffered a heart attack in the previous month.

Some 17 patients received coronary artery infusions of 12 to 25 million stem cells derived from healthy tissue taken from their own hearts. The remaining eight underwent standard post-heart attack care.

A year later, the proportion of the heart left scarred in the stem cell-treated patients had been reduced from 24 per cent to 12 per cent. No change was seen in patients who did not receive the treatment.

Professor Eduardo Marban, director of the Cedars-Sinai Heart Institute in Los Angeles, who led the US team, said: “The effects are substantial, and surprisingly larger in humans than they were in animal tests.

“This discovery challenges the conventional wisdom that, once established, scar is permanent and that, once lost, healthy heart muscle cannot be restored.”

The Phase I study, which was chiefly conducted to evaluate safety, was published today in an online edition of the Lancet.  It follows a similar trial by US scientists at Harvard Medical School and the University of Louisville whose findings were reported last year, also in the Lancet.

That study, which used a different kind of heart stem cell, produced a 12 per cent average increase in ejection fraction.

Yet another breakthrough for ethical adult stem cells.

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Neurosurgeon calls Mark Levin show and explains what Obamacare really does

I found this on my friend Wes’ Facebook page.

Consider this news story from the UK, where they have a massive state-run health care system called the National Health Service.

Excerpt:

A young woman who is starving to death after being diagnosed with a paralysed stomach has been told that NHS bosses refuse to fund an operation to save her.

Rudi Hargreaves, 22, has shrunk from a healthy 10st to a skeletal 5st 10lb after being diagnosed with the crippling condition last year.

Within weeks of being diagnosed with gastroparesis, Rudi found her size 12 clothes were hanging off her – as her stomach became unable to digest food at a normal rate.

The condition can be treated with a £14,000 operation to fit a gastric pacemaker – although this is still considered to be an experimental treatment.

But health chiefs have refused to fund the surgery, saying ‘insufficient supporting information’ has been provided by her GP.

[…]A spokesperson for NHS Hull said: ‘To date, the application in question has not been agreed as, crucially, insufficient supporting information has been provided to allow due consideration to take place.

‘Any requested procedures must also fall in line with the provider trust’s priorities for service development and delivery.

‘The patient’s clinician has been invited to provide the necessary clarification, receipt of which should enable the patient’s case to be progressed within the PCT.’

What’s even more troubling is the situation in countries like Canada, where the government decides whether you will be treated. And worse, if they deny you treatment, you cannot pay for treatment out of pocket. You have to leave the country and pay someone else out of pocket for the treatment, even though you have have already paid some huge amount of your earned income into the system for many years – which will go to treat other people who need abortions, breast implants , sex changes and IVF. So your money is good enough for them to collect over your life, but when you need treatment, you may not be allowed to get it, and you may not even have the money (after taxes) to go abroad for treatment.

Liberal media silent as ESCR pioneer Geron halts ESCR research

Here’s the story from CBS News.

Excerpt:

The company doing the first government-approved test of embryonic stem cell therapy is discontinuing further stem cell work, a move with stark implications for a field offering hope of future medicines for conditions with inadequate or no current treatments.

Geron Corp., a pioneer in stem cell research that has been testing a spinal cord injury treatment, said late Monday that it’s halting development of its stem cell programs to conserve funds. It is seeking partners to take on the programs’ assets and is laying off much of its staff.

[…]The company is eliminating 66 full-time jobs, or 38 percent of its staff, a process that will bring about $8 million in costs— about $5 million in the current quarter and about $3 million in the first half of 2012.

Now consider this article in the Weekly Standard by Wesley J. Smith. (H/T ECM)

Excerpt:

For years, the media touted the promise of embryonic stem cells. Year after year, Geron Corporation announced that its embryonic stem cell treatment for acute spinal cord injury would receive FDA approval “next year” for human testing. And year after year, the media dutifully informed readers and viewers that cures were imminent. When the FDA finally did approve a tiny human trial for 10 patients in January 2009, the news exploded around the world. This was it: The era of embryonic stem cell therapy had arrived!

Not exactly. Last week, Geron issued a terse statement announcing it was not only canceling the study, but abandoning the embryonic stem cell field altogether for financial reasons.

You would think Geron’s failure would be very big news. Instead, it turns out that the mainstream media pay attention only when embryonic stem cell research seems to be succeeding—so far, almost exclusively in animal studies. When, as here, it crashes and burns, it is scarcely news at all.

[M]ost of the same news outlets that gave Geron star treatment when it was heralding supposed breakthroughs provided only muted coverage of the company’s retreat into producing anti-cancer drugs.

The Los Angeles Times may be the most egregious offender. A chronic booster of Geron’s embryonic stem cell research, it reported the FDA’s approval of a human trial on January 24, 2009, in a story that began, “Ushering in a new era in medicine .  .  . ” The paper stayed on the story. In October 2010, it reported that the first patient had received an injection, then a few days later it ran a feature about the study under the headline “Hope for Spinal Cord Patients.” During the same period, however, the paper did not report the encouraging results of early human trials of treatments for spinal cord injury developed using adult stem cells.

Then last May, the Times celebrated the California Institute of Regenerative Medicine’s $25 million loan to support Geron’s study, noting that the company’s stem cell product had performed as hoped in rat -studies. Yet the day after Geron’s embryonic stem cell research unit was laid off, the Times couldn’t find the space to print the story, though the following day a blog entry ran on the Times website.

The vast majority (all?) of medical successes with stem cell research have come from ethical adult stem-cell research. Adult stem cell research does not kill unborn children. And that’s why it doesn’t draw funding from pro-abortion politicians or get positive coverage by pro-abortion media outlets. The politics is driving the science – just like with global warming research and alternative energy funding.

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