Tag Archives: Multiple Sclerosis

New study: oral contraceptives linked to higher risk of multiple sclerosis

ECM sent me this article from Fox News about the new study.

Excerpt:

In a new study, researchers found an increased risk of multiple sclerosis (MS) among women who have taken oral contraceptives. However, the findings do not mean women should stop using birth control, the researchers say.

Utilizing membership data from Kaiser Permanente Southern California, researchers analyzed the health records of 305 women aged 14 to 48 who were diagnosed with MS or its precursor, clinically isolated syndrome (CIS), between 2008 and 2011.  They looked at the women’s birth control use up to three years prior to the onset of MS symptoms

Overall, researchers found a 30 percent increased risk of developing MS amongst women who had at least three months of oral contraceptive use, compared to a control group of 3,050 women who did not have MS. They found that 29.2 percent of women with MS used birth control before their diagnoses, while 23 percent of women in the healthy control group used birth control– showing an increased risk with higher use of the drug, study author Dr. Kerstin Hellwig, a post-doctoral research fellow at Kaiser Permanente Southern California, told FoxNews.com.

Additionally, for women who did not currently use an oral contraceptive but had in some time in the three years prior to being diagnosed, there was also a slightly higher risk.

Multiple sclerosis is an autoimmune disease affecting the central nervous system. The causes are unclear, but experts believe genetics, environmental hazards and smoking are all possible factors. The condition normally develops between ages 20 and 40, Hellwig said.

Researchers say use of birth control is not a firmly established cause for MS, but they do see a link.

“It’s not clear what role [hormones] play in the development of the disease, but it’s clear that two to three times more women than men have MS,” Hellwig said.

Previously, I blogged about studies on abortion and breast cancer.

Abortion and breast cancer

New study is up here at the National Institutes of Health web site.

Life News reported on the study here.

Excerpt:

A new study of women from India shows women who get an induced abortion are 626% more likely to have breast cancer compared with women who carry their pregnancies to term and have the baby.The study found women more likely to have breast cancer had “higher number of abortions.”

This study follows closely after a bombshell meta-analysis of breast cancer studies found a 44% increased risk of contracting breast cancer for women who had abortions.

“History of abortion was also found to be positively associated with the risk of breast cancer with 6.26 times higher risk in women having a history of abortion,” they concluded.

The doctors conducting the new study are based at the Department of Gastroenterology and Human Nutrition Unit, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India. Their report, published in the Indian Journal of Cancer confirms what previous studies have shown, namely that an abortion weakens the breast’s muscle tissue in a way that makes it more susceptible to cancer.

“However, the cases had a significantly higher number of abortions (61.3%) as compared to the controls (16.3%),” they wrote. “History of abortion was also found to be positively associated with the risk of breast cancer with 6.26 times higher risk in women having a history of abortion. The history of abortions was found to be significantly higher in breast cancer cases as compared to controls, with the Relative Risk (RR) = 6.26 in women having a history of abortion.”

This is not the first study to confirm a link between abortion and breast cancer.

Abortion and breast cancer

Many studies show a link between abortion and breast cancer.

Study 1: (September 2010)

Based on the expression of estrogen receptor (ER), progesterone receptor (PR) and HER2/neu (HER2), breast cancer is classified into several subtypes: luminal A (ER+ and/or PR+, HER2-), luminal B (ER+ and/or PR+, HER2+), HER2-overexpressing (ER-, PR-, and HER2+) and triple-negative (ER-, PR-, and HER2-). The aim of this case-control study is to determine reproductive factors associated with breast cancer subtypes in Chinese women. A total of 1,417 patients diagnosed with breast cancer in the First Affiliated Hospital, China Medical University, Shenyang, China between 2001 and 2009 and 1,587 matched controls without a prior breast cancer were enrolled.

[…]Postmenopause and spontaneous abortion were inversely associated with the risk of luminal tumors. By contrast, multiparity, family history of breast cancer and induced abortion increased the risk of breast cancer.

Study 2: (March 2010)

OBJECTIVE: To explore the risk factors of breast cancer for better control and prevention of the malignancy.

METHODS: The clinical data of 232 patients with pathologically established breast cancer were investigated in this 1:1 case-control study to identify the risk factors of breast cancer.

RESULTS: The history of benign breast diseases, family history of carcinoma andmultiple abortions were the statistically significant risk factors of breast cancer, while breast feeding was the protective factor.

CONCLUSION: A history of benign breast diseases, family history of carcinoma and multiple abortions are all risk factors of breast cancer.

And more recently, I blogged about a very recent study from China which concluded thus:

IA is significantly associated with an increased risk of breast cancer among Chinese females, and the risk of breast cancer increases as the number of IA increases. If IA were to be confirmed as a risk factor for breast cancer, high rates of IA in China may contribute to increasing breast cancer rates.

IA is, of course, induced abortion.